ArticleNature communications2015
Multiparametric AFM reveals turgor-responsive net-like peptidoglycan architecture in live streptococci.
Article in Nature communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 62 citations in OpenAlex.
- Adaptive remodeling of cell wall peptidoglycan architecture inFood chemistry: X · 2026Article
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- From biogenesis to host modulation: the expanding biology of oral streptococcal membrane vesicles.FEMS microbiology reviews · 2026Review
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- Surveying membrane landscapes: a new look at the bacterial cell surface.Nature reviews. Microbiology · 2023Review
- Effect of decoration route on the nanomechanical, adhesive, and force response of nanocelluloses-An in situ force spectroscopy study.PloS one · 2023Article
- Study of tribological properties of human buccal epithelium cell membranes using probe microscopy.Scientific reports · 2022Article
- A Comparison of the Adaptive Response ofFrontiers in microbiology · 2022Article
- Management ofFoods (Basel, Switzerland) · 2021Article
- Structural Visualization of Septum Formation in Staphylococcus warneri Using Atomic Force Microscopy.Journal of bacteriology · 2020Article
- Near Simultaneous Laser Scanning Confocal and Atomic Force Microscopy (Conpokal) on Live Cells.Journal of visualized experiments : JoVE · 2020Article
- Mechanical penetration of β-lactam-resistant Gram-negative bacteria by programmable nanowires.Science advances · 2020Article
- Volcano-Shaped Scanning Probe Microscopy Probe for Combined Force-Electrogram Recordings from Excitable Cells.Nano letters · 2020Article
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- Alterations in the Cell Wall ofFrontiers in microbiology · 2020Article
- Overlapping and essential roles for molecular and mechanical mechanisms in mycobacterial cell division.Nature physics · 2020Article
- Microscopic Investigation of the Combined Use of Antibiotics and Biosurfactants on Methicillin ResistantFrontiers in microbiology · 2020Article
- Microbial adhesion and ultrastructure from the single-molecule to the single-cell levels by Atomic Force Microscopy.Cell surface (Amsterdam, Netherlands) · 2019Review
- Direct observation of the cell-wall remodeling in adheringCell surface (Amsterdam, Netherlands) · 2019Review
- Variation of Burkholderia cenocepacia cell wall morphology and mechanical properties during cystic fibrosis lung infection, assessed by atomic force microscopy.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell-wall peptidoglycan (PG) of Gram-positive bacteria is a strong and elastic multi-layer designed to resist turgor pressure and determine the cell shape and growth. Despite its crucial role, its architecture remains largely unknown. Here using high-resolution multiparametric atomic force microscopy (AFM), we studied how the structure and elasticity of PG change when subjected to increasing turgor pressure in live Group B Streptococcus. We show a new net-like arrangement of PG, which stretches and stiffens following osmotic challenge. The same structure also exists in isogenic mutants lacking surface appendages. Cell aging does not alter the elasticity of the cell wall, yet destroys the net architecture and exposes single segmented strands with the same circumferential orientation as predicted for intact glycans. Together, we show a new functional PG architecture in live Gram-positive bacteria.
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