ArticlePloS one2015
Gap Effect Abnormalities during a Visually Guided Pro-Saccade Task in Children with Attention Deficit Hyperactivity Disorder.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Transdiagnostic eye-tracking biomarkers of inattention across psychiatric disorders: a systematic review.BMC psychiatry · 2025Pooled it
- The brain anatomy of attention-deficit/hyperactivity disorder in young adults - a magnetic resonance imaging study.PloS one · 2017Trial
- Unified modelling of gaze and pupil dynamics in saccadic tasks.Scientific reports · 2026Article
- Pattern of Oculomotor Findings in Children with Attention Deficit/Hyperactivity Disorder in Relation to Methylphenidate Treatment.Journal of clinical medicine · 2026Review
- Cognition and saccadic eye movement performance are impaired in chronic rhinosinusitis.International forum of allergy & rhinology · 2024Article
- Table tennis players use superior saccadic eye movements to track moving visual targets.Frontiers in sports and active living · 2024Article
- Maturational Indices of the Cognitive Control Network Are Associated with Inhibitory Control in Early Childhood.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Eye Movement Alterations in Post-COVID-19 Condition: A Proof-of-Concept Study.Sensors (Basel, Switzerland) · 2022Article
- Article
- Distribution of Visual and Oculomotor Alterations in a Clinical Population of Children with and without Neurodevelopmental Disorders.Brain sciences · 2021Article
- Can auditory warning signals normalize eye movements in children with ADHD?European child & adolescent psychiatry · 2020Article
- Clinical Characterization of Oculomotricity in Children with and without Specific Learning Disorders.Brain sciences · 2020Article
- Back to basics: The effects of block vs. interleaved trial administration on pro- and anti-saccade performance.PloS one · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that starts in early childhood and has a comprehensive impact on psychosocial activity and education as well as general health across the lifespan. Despite its prevalence, the current diagnostic criteria for ADHD are debated. Saccadic eye movements are easy to quantify and may be a quantitative biomarker for a wide variety of neurological and psychiatric disorders, including ADHD. The goal of this study was to examine whether children with ADHD exhibit abnormalities during a visually guided pro-saccadic eye-movement and to clarify the neurophysiological mechanisms associated with their behavioral impairments. Thirty-seven children with ADHD (aged 5-11 years) and 88 typically developing (TD) children (aged 5-11 years) were asked to perform a simple saccadic eye-movement task in which step and gap conditions were randomly interleaved. We evaluated the gap effect, which is the difference in the reaction time between the two conditions. Children with ADHD had a significantly longer reaction time than TD children (p < 0.01) and the gap effect was markedly attenuated (p < 0.01). These results suggest that the measurement of saccadic eye movements may provide a novel method for evaluating the behavioral symptoms and clinical features of ADHD, and that the gap effect is a potential biomarker for the diagnosis of ADHD in early childhood.
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