Evidence map›Paper›PMID 26017894›Full record

ArticleInternational urogynecology journal2015

Does preoperative anal physiology testing or ultrasonography predict clinical outcome with sacral neuromodulation for fecal incontinence?

Yarini Quezada, James L Whiteside, Tracy Rice, Mickey Karram, Janice F Rafferty, Ian M Paquette

Abstract read
In one paragraph

Article in International urogynecology journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Fecal incontinence - Challenges and solutions.World journal of gastroenterology · 2017
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yarini QuezadaDivision of Female Pelvic Medicine and Reconstructive Surgery, The Christ Hospital Department of Obstetrics and Gynecology, Cincinnati, OH, USA.
James L WhitesideDepartment of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Tracy RiceDepartment of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Mickey KarramDivision of Female Pelvic Medicine and Reconstructive Surgery, The Christ Hospital Department of Obstetrics and Gynecology, Cincinnati, OH, USA.
Janice F RaffertyDepartment of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Ian M PaquetteDepartment of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA. ian.paquette@uc.edu.
University of Cincinnati Medical Center · USChrist Hospital · US

Funding

HOST RESPONSE TO TRAUMA RESEARCH TRAINING PROGRAMT32GM008478 · NIGMS · UNIVERSITY OF CINCINNATI · PI TIMOTHY A PRITTS, BASILIA ZINGARELLI · 1993 to 2026
$6.7M
NIGMS NIH HHS T32 GM008478
6 · The paper itself

Abstract

introduction and hypothesisTo determine the value of preoperative anal physiology testing and transanal ultrasonography in predicting clinical response to sacral neuromodulation for fecal incontinence.

methodsWe report a retrospective study of all patients treated with sacral neuromodulation for fecal incontinence in a single practice between 2011 and 2014 was performed. Patient demographics included age, gender, comorbidities, presence of an ultrasound-defined external sphincter defect, and history of prior anal sphincter repair. Cleveland Clinic Florida (CCF) scores were used to assess the severity of fecal incontinence at baseline, and at 3, 6 and 12 months. Pearson's correlation coefficient was used to evaluate the relationship between preoperative physiology testing and ultrasonography and patient outcome.

resultsSacral neuromodulation was trialed in 60 patients, of whom 31 had anorectal physiology testing and 29 did not. Patients who were tested were younger (60.9 vs. 71.4 years, p = 0.013) and more likely to have had a prior overlapping sphincteroplasty (40.5% vs. 15%, p = 0.043). Among patients who progressed to complete system implantation, CCF scores at 3 and 12 months were similar whether they had physiology testing or not. Likewise, patient outcome did not correlate with the finding of an ultrasound-defined external sphincter defect. Pearson's correlation coefficient was used to evaluate the relationship between the test results and the 3-month CCF scores. CCF scores 3 months after full system implantation did not correlate with the presence or size of an external sphincter defect, resting or squeeze pressure, pudendal nerve terminal motor latency, rectoanal inhibitory reflex, or minimum detectable volume.

conclusionsAnal physiology testing and ultrasonography were not predictive of clinical outcomes among patients treated with sacral neuromodulation for fecal incontinence.

Indexed as

Neurosurgical ProceduresAgedAnal CanalFecal IncontinenceFemaleHumansMaleMiddle AgedPreoperative CareRetrospective StudiesUltrasonographyFecalIncontinenceNeuromodulation

Identifiers

PMID26017894
PMCPMC5103307
OpenAlexW362590651

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.