ArticleClinics (Sao Paulo, Brazil)2015
Is local resection sufficient for parathyroid carcinoma?
Article in Clinics (Sao Paulo, Brazil), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Critical Insights into Parathyroid Cancer.Journal of cancer science and clinical therapeutics · 2026Article
- Left supraclavicular parathyroid carcinoma: diagnostic difficulties through a case report.The Pan African medical journal · 2024Article
- Article
- Association of Parathyroid and Differentiated Thyroid Carcinomas: A Narrative Up-To-Date Review of the Literature.Medicina (Kaunas, Lithuania) · 2022Review
- Case series of diagnosis and surgery challenges in parathyroid carcinoma.International journal of surgery case reports · 2022Article
- Local resection versus radical surgery for parathyroid carcinoma: A National Cancer Database analysis.European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology · 2021Article
- An Unusual Simultaneous Existence of Parathyroid Carcinoma and Papillary Thyroid Carcinoma: Case Report and Review of Literature.Case reports in endocrinology · 2020Article
- Review
- Nonfunctional double parathyroid carcinoma with incidental thyroid micropapillary carcinoma: a rare case.The Pan African medical journal · 2017Article
- [Parathyroid carcinoma: about a case and review of the literature].The Pan African medical journal · 2017Review
- Intact parathormone measurement 1 hour after total thyroidectomy as a predictor of symptomatic hypocalcemia.International journal of clinical and experimental medicine · 2015Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesParathyroid carcinoma is a rare malignant disease of the parathyroid glands that appears in less than 1% of patients with primary hyperparathyroidism. In the literature, the generally recommended treatment is en bloc tumor excision with ipsilateral thyroid lobectomy. Based on our 12 years of experience, we discuss the necessity of performing thyroid lobectomy on parathyroid carcinoma patients.
resultsEleven parathyroid carcinoma cases were included in the study. All operations were performed at the Department of Endocrine Surgery at Ankara University Medical School. Seven of the patients were male (63.6%), and the mean patient age was 48.9 ± 14.0 years. Hyperparathyroidism was the most common indication for surgery (n ϝ 10, 90.9%). Local disease was detected in 5 patients (45.5%), invasive disease was detected in 5 patients (45.5%) and metastatic disease was detected in 1 patient (9.1%). The mean follow-up period was 99.6 ± 42.1 months, and the patients' average disease-free survival was 96.0 ± 49.0 months. During the follow-up period, only 1 patient died of metastatic parathyroid carcinoma.
conclusionParathyroid carcinoma has a slow-growing natural progression, and regional lymph node metastases are uncommon. Although our study comprised few patients, it nevertheless showed that in selected cases, parathyroid carcinoma could be solely treated with parathyroidectomy.
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