Evidence map›Paper›PMID 26017768›Full record

ArticleDevelopmental cell2015

A Notch above Sonic Hedgehog.

Odessa Yabut, Samuel J Pleasure, Keejung Yoon

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Odessa YabutDepartment of Neurology, Programs in Neuroscience and Developmental and Stem Cell Biology, Institute for Regenerative Medicine, University of California San Francisco, San Francisco, CA 94158.
Samuel J PleasureDepartment of Neurology, Programs in Neuroscience and Developmental and Stem Cell Biology, Institute for Regenerative Medicine, University of California San Francisco, San Francisco, CA 94158. Electronic address: sam.pleasure@ucsf.edu.
Keejung YoonDepartment of Neurology, Programs in Neuroscience and Developmental and Stem Cell Biology, Institute for Regenerative Medicine, University of California San Francisco, San Francisco, CA 94158; College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon, Gyeonggi-do 440-746, Republic of Korea.
University of California, San Francisco · US

Funding

SDF1/CXCR4 Signaling and Tangential Neuronal Migration in the Developing CortexR01MH077694 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PLEASURE, SAMUEL JEREMY · 2007 to 2019
$5.0M
6 · The paper itself

Abstract

Cell fate specification requires tightly orchestrated cellular responses to extracellular factors. In this issue of Developmental Cell, Kong et al. (2015) reveal that Notch signaling activity facilitates the interpretation of Sonic hedgehog (Shh) signals by regulating signaling in the cilia, influencing fate specification of neural stem and progenitor cells.

Indexed as

Cell DifferentiationAnimalsCiliaHedgehog ProteinsNeural Stem CellsNeurogenesisReceptors, NotchStem CellsHedgehog ProteinsReceptors, Notch

Identifiers

PMID26017768
OpenAlexW2165058923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.