ArticleEuropean radiology2016
Feasibility of mesorectal vascular invasion in predicting early distant metastasis in patients with stage T3 rectal cancer based on rectal MRI.
Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Early MRI predictors of disease-free survival in locally advanced rectal cancer from the GRECCAR 4 trial.The British journal of surgery · 2019Trial
- Histogram analysis of dynamic contrast-enhanced magnetic resonance imaging to predict extramural venous invasion in rectal cancer.BMC medical imaging · 2023Article
- Radiomics based on preoperative rectal cancer MRI to predict the metachronous liver metastasis.Abdominal radiology (New York) · 2023Article
- The prognostic value of extramural venous invasion in preoperative MRI of rectal cancer patients.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022Article
- An endorectal ultrasound-based radiomics signature for preoperative prediction of lymphovascular invasion of rectal cancer.BMC medical imaging · 2022Article
- Predictive factors for early distant metastasis after neoadjuvant chemoradiotherapy in locally advanced rectal cancer.World journal of gastrointestinal oncology · 2021Article
- MRI-based radiomics nomogram to predict synchronous liver metastasis in primary rectal cancer patients.Cancer medicine · 2020Article
- The prognostic significance of MRI-detected extramural venous invasion, mesorectal extension, and lymph node status in clinical T3 mid-low rectal cancer.Scientific reports · 2019Article
- MRI radiomics analysis for predicting preoperative synchronous distant metastasis in patients with rectal cancer.European radiology · 2019Article
- Article
- MRI-based Radiomics nomogram to detect primary rectal cancer with synchronous liver metastases.Scientific reports · 2019Article
- Magnetic Resonance Imaging-Detected Extramural Venous Invasion in Rectal Cancer before and after Preoperative Chemoradiotherapy: Diagnostic Performance and Prognostic Significance.European radiology · 2018Article
- Chemical shift effect predicting lymph node status in rectal cancer using high-resolution MR imaging with node-for-node matched histopathological validation.European radiology · 2017Article
- Prognostic aspects of dynamic contrast-enhanced magnetic resonance imaging in synchronous distant metastatic rectal cancer.European radiology · 2017Observational
- Non-invasive MR assessment of macroscopic and microscopic vascular abnormalities in the rectal tumour-surrounding mesorectum.European radiology · 2016Article
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6 authors.
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Abstract
objectivesTo evaluate the feasibility of mesorectal vascular invasion (MVI) in predicting early distant metastasis developed within 1 year of diagnosis of T3 rectal cancer using magnetic resonance imaging (MRI)
methodsSixty-five patients with T3 rectal cancer (early metastasis, n = 28; non-metastasis, n = 37) were enrolled in this study. Early distant metastases developed in 28 patients (liver, n = 15; lung, n = 9; both, n = 4). Logistic regression was used to determine the independent predictors for early distant metastasis.
resultsIn univariate analysis, tumour location, carcinoembryonic antigen (CEA), lymphovascular invasion (LVI), MRI-detected MVI, and mesorectal fat infiltration (MFI) (odds ratio [OR], 4.533, 9.583, 5.539, 27.046, and 5.539, respectively) were associated with early distant metastasis. Multivariate analysis demonstrated that MVI (OR, 29.949; P < 0.002) and LVI (OR, 6.684; P = 0.033) were independent factors for early distant metastasis. Specificity and positive predictive value (PPV) of MVI (94.59%, and 89.47%, respectively) were significantly higher than those of LVI (64.86%, and 61.76%), but sensitivity and negative predictive value were not significantly different between MVI (60.71%, and 76.09%) and LVI (75.00%, and 77.42%).
conclusionsWhile sensitivity of MRI-detected MVI was equal to that of CEA in predicting early distant metastasis from T3 rectal cancer, specificity and PPV may be improved by assessing MVI. KEY POINTS: • Mesorectal vascular invasion (MVI) may be a radiologic prognostic factor for rectal cancer. • Specificity of MVI was higher than lymphovascular invasion in predicting early metastasis. • Mesorectal vascular invasion may be a better predictor for early distant metastasis.
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