Evidence map›Paper›PMID 26017734›Full record

ArticleEuropean radiology2015

PET/MRI and PET/CT in advanced gynaecological tumours: initial experience and comparison.

Marcelo A Queiroz, Rahel A Kubik-Huch, Nik Hauser, Bianka Freiwald-Chilla, Gustav von Schulthess, Johannes M Froehlich, Patrick Veit-Haibach

Open access · greenAbstract readComparative StudyEvaluation Study
PubMed Publisher
In one paragraph

Article in European radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 6 pooled it
21.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 6 syntheses or guidelines pooled it, 126 citations in OpenAlex.

  1. Diagnostic performance of whole-body [European radiology · 2024
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  3. EANM/SNMMI practice guideline for [European journal of nuclear medicine and molecular imaging · 2021
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  15. International EANM-SNMMI-ISMRM consensus recommendation for PET/MRI in oncology.European journal of nuclear medicine and molecular imaging · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Marcelo A QueirozDepartment Medical Radiology, Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.
Rahel A Kubik-Huch
Nik Hauser
Bianka Freiwald-Chilla
Gustav von Schulthess
Johannes M Froehlich
Patrick Veit-Haibach
Kantonsspital Baden · CHUniversity Hospital of Zurich · CHUnion Bank of Switzerland · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the diagnostic accuracy of PET/MRI and PET/CT for staging and re-staging advanced gynaecological cancer patients as well as identify the potential benefits of each method in such a population. MATERIAL AND

methodsTwenty-six patients with suspicious or proven advanced gynaecological cancer (12 ovarian, seven cervical, one vulvar and four endometrial tumours, one uterine metastasis, and one primary peritoneal cancer) underwent whole-body imaging with a sequential trimodality PET/CT/MR system. Images were analysed regarding primary tumour detection and delineation, loco-regional lymph node staging, and abdominal/extra-abdominal distant metastasis detection (last only by PET/CT).

resultsEighteen (69.2 %) patients underwent PET/MRI for primary staging and eight patients (30.8 %) for re-staging their gynaecological malignancies. For primary tumour delineation, PET/MRI accuracy was statistically superior to PET/CT (p < 0.001). Among the different types of cancer, PET/MRI presented better tumour delineation mainly for cervical (6/7) and endometrial (2/3) cancers. PET/MRI for local evaluation as well as PET/CT for extra-abdominal metastases had therapeutic consequences in three and one patients, respectively. PET/CT detected 12 extra-abdominal distant metastases in 26 patients.

conclusionPET/MRI is superior to PET/CT for primary tumour delineation. No differences were found in detection of regional lymph node involvement and abdominal metastases detection. KEY POINTS: • PET/MRI is superior to PET/CT for primary tumour delineation • PET/CT represents a reliable tool to detect extra-abdominal distant metastasis • PET/MRI might be the preferred imaging modality for staging cervical and endometrial tumours • Whole-body staging for detection and evaluation of extra-abdominal metastases is mandatory.

Indexed as

AdultAgedAged, 80 and overFemaleFluorodeoxyglucose F18Genital Neoplasms, FemaleHumansLymphatic MetastasisLymph NodesMagnetic Resonance ImagingMiddle AgedMultimodal ImagingNeoplasm MetastasisNeoplasm StagingPositron-Emission TomographyProspective StudiesFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID26017734
OpenAlexW401734848

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.