ArticleBMC genomics2015
Early life microbial colonization of the gut and intestinal development differ between genetically divergent broiler lines.
Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
76 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Plasticity of intestinal gene expression profile signatures reflected by nutritional interventions in piglets.BMC genomics · 2019Pooled it
- Feeder- and Drinker-Associated Microbiota Differ from Host-Associated Fecal Microbiota During a Commercial Broiler Production Cycle with Age-Associated Changes in Taxonomic Composition.Animals : an open access journal from MDPI · 2026Article
- The Artificial-Feeding System with a Lactic Acid Bacteria-Fermented Diet, Compared with Parent Feeding, Is Associated with Tract-Wide Microbiota Shifts and Coordinated Developmental Indices in Squabs.Animals : an open access journal from MDPI · 2026Article
- Unraveling the differences in meat flavor of duck and its regulatory mechanisms based on microbiomics, metabolomics, and flavoromics sequencing.Current research in food science · 2026Article
- Embryonic thermal manipulation improved early cecal microbial diversity, metabolic pathways, and immunity in broiler chickens.Scientific reports · 2025Article
- The chicken gut microbiome in conventional and alternative production systems.Journal of animal science and biotechnology · 2025Review
- Restricted vs. ad libitum feeding during sow gestation affects piglet performance, behavior, and fecal microbiota composition.Journal of animal science · 2025Article
- Co-housing with Tibetan chickens improved the resistance of Arbor Acres chickens to Salmonella enterica serovar Enteritidis infection by altering their gut microbiota composition.Journal of animal science and biotechnology · 2025Article
- Influence of a multi-strain probiotic and zinc-glycine chelate, administeredFrontiers in physiology · 2025Article
- Impact of Chlorella vulgaris and probiotic supplementation on performance, immunity and intestinal microbiota of broiler chickens.PloS one · 2025Article
- Impact ofPathogens (Basel, Switzerland) · 2024Article
- Improving broiler health through cecal microbiota transplantation: a comprehensive study on growth, immunity, and microbial diversity.Journal of animal science · 2024Article
- Gut Microbial Diversity Analysis of Different Native Chickens and Screening of Chicken-Derived Probiotics.Animals : an open access journal from MDPI · 2023Article
- Dietary supplementation of zinc oxide modulates intestinal functionality during the post-weaning period in clinically healthy piglets.Journal of animal science and biotechnology · 2023Article
- Cecal microbiota composition differs under normal and high ambient temperatures in genetically distinct chicken lines.Scientific reports · 2023Article
- Dynamic Changes in the Gut Microbiota and Metabolites during the Growth of Hainan Wenchang Chickens.Animals : an open access journal from MDPI · 2023Article
- Article
- Host genotype affects endotoxin release in excreta of broilers at slaughter age.Frontiers in genetics · 2023Article
- Differences in gut bacterial community composition between modern and slower-growing broiler breeder lines: Implications of growth selection on microbiome composition.Frontiers in physiology · 2023Article
- Physiological effects ofFrontiers in veterinary science · 2023Review
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHost genetic makeup plays a role in early gut microbial colonization and immune programming. Interactions between gut microbiota and host cells of the mucosal layer are of paramount importance for a proper development of host defence mechanisms. For different livestock species, it has already been shown that particular genotypes have increased susceptibilities towards disease causing pathogens. The objective of this study was to investigate the impact of genotypic variation on both early microbial colonization of the gut and functional development of intestinal tissue. From two genetically diverse chicken lines intestinal content samples were taken for microbiota analyses and intestinal tissue samples were extracted for gene expression analyses, both at three subsequent time-points (days 0, 4, and 16).
resultsThe microbiota composition was significantly different between lines on each time point. In contrast, no significant differences were observed regarding changes in the microbiota diversity between the two lines throughout this study. We also observed trends in the microbiota data at genus level when comparing lines X and Y. We observed that approximately 2000 genes showed different temporal gene expression patterns when comparing line X to line Y. Immunological related differences seem to be only present at day 0, because at day 4 and 16 similar gene expression is observed for these two lines. However, for genes involved in cell cycle related processes the data show higher expression over the whole course of time in line Y in comparison to line X.
conclusionsThese data suggest the genetic background influences colonization of gut microbiota after hatch in combination with the functional development of intestinal mucosal tissue, including the programming of the immune system. The results indicate that genetically different chicken lines have different coping mechanisms in early life to cope with the outside world.
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