ArticleEuropean child & adolescent psychiatry2016
Psychotropic medicine prescriptions in Italian youths: a multiregional study.
Article in European child & adolescent psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Prescription prevalence of psychotropic drugs in children and adolescents: an analysis of international data.European journal of clinical pharmacology · 2019Pooled it
- Can Adjunctive Lithium Therapy Influence Emotional Dysregulation in Adolescents? Findings from a Retrospective Study.Journal of clinical medicine · 2025Article
- Impact of COVID-19 pandemic on prescription of psychotropic medications in the Italian paediatric population during 2020.Italian journal of pediatrics · 2024Article
- Prevalence of use of on-label and off-label psychotropics in the Greek pediatric population.Frontiers in pharmacology · 2024Article
- Trends in Prescribing Antipsychotics for Children and Adolescents in Japan: A Descriptive Epidemiological Study Using a Large-Scale Pharmacy Dataset.Child psychiatry and human development · 2023Article
- Utilisation of drugs for the treatment of psychiatric diseases in the pediatric population: focus on off-label use.Frontiers in pharmacology · 2023Article
- ADHD diagnosis and methylphenidate consumption in children and adolescents: A systematic analysis of health databases in France over the period 2010-2019.Frontiers in psychiatry · 2022Article
- Psychotropic use in children and adolescents in Scandinavia and Catalonia: a 10-year population-based study.Psychopharmacology · 2021Article
- Risk factors for low adherence to methylphenidate treatment in pediatric patients with attention-deficit/hyperactivity disorder.Scientific reports · 2021Article
- 'Use of antipsychotics in children and adolescents: a picture from the ARITMO population-based European cohort study'.Epidemiology and psychiatric sciences · 2020Article
- Traceability of Pediatric Antibiotic Purchasing Pathways in Italy: A Nationwide Real-World Drug Utilization Analysis.Frontiers in pharmacology · 2020Article
- New Users of Antipsychotics Among Children and Adolescents in 2008-2017: A Nationwide Register Study.Frontiers in psychiatry · 2020Article
- Prevalence, incidence and persistence of ADHD drug use in Japan.Epidemiology and psychiatric sciences · 2019Article
- Do autistic patients change healthcare services utilisation through the transition age? An Italian longitudinal retrospective study.BMJ open · 2019Article
- The evidence-based choice for antipsychotics in children and adolescents should be guaranteed.European journal of clinical pharmacology · 2019Review
- The Role of European Healthcare Databases for Post-Marketing Drug Effectiveness, Safety and Value Evaluation: Where Does Italy Stand?Drug safety · 2019Review
- The predictive value of ABCB1, ABCG2, CYP3A4/5 and CYP2D6 polymorphisms for risperidone and aripiprazole plasma concentrations and the occurrence of adverse drug reactions.The pharmacogenomics journal · 2018Article
- Psychopharmacological Prescriptions in Children and Adolescents in Germany.Deutsches Arzteblatt international · 2016Article
- Update on the safety of second generation antipsychotics in youths: a call for collaboration among paediatricians and child psychiatrists.Italian journal of pediatrics · 2016Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to evaluate the trend of paediatric psychotropic drug prescriptions in Italy. Data sources were regional, outpatient prescription databases. Seven Italian regions, covering 50 % of the Italian population, provided data from 2006 to 2011. Prevalence and incidence of prescriptions by age and gender were evaluated for psychotropic, antidepressant, antipsychotic, and attention-deficit/hyperactivity disorders (ADHD) medications. The hospital admission rate for psychiatric conditions was calculated, also at the local health unit (LHU) level. The presence of trends in prescription prevalence and incidence during the 6 year period was assessed. Finally, the correlation between prevalence, prescription, hospital admission rates, latitude, longitude, and average annual income at the LHU level was also investigated. In 2011, 8834 youths received at least one psychotropic drug prescription, with a prevalence of 1.76 ‰ (95 % CI 1.72-1.80). The incidence of new psychotropic drug users was 1.03 ‰ (1.00-1.06). The prevalence of antidepressants was 1.02 ‰ (0.99-1.04), while that of antipsychotics was 0.70 ‰ (0.68-0.72), and that of ADHD medications 0.19 ‰ (0.18-0.21). The psychotropic drug prevalence increased with increasing age. Males were more exposed to psychotropic drugs than females (AUC0-17 male/female = 1.23). Antipsychotics were the most prescribed psychotropic drugs in males, while antidepressants were in females. Between-region prevalence ranged from 1.56 to 2.17 ‰. The overall prevalence of psychotropic drug from 2006 to 2011 was stable (χ(t)2 ≤ 0.001, p = 0.97). No correlation was found between prevalence and the variables investigated. Psychotropic drug prescription was very limited and stable. No geographical patterns were found.
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