Evidence map›Paper›PMID 26015924›Full record

ArticleAdvanced biomedical research2015

Venous insufficiency after prolonged standing: Is joint hypermobility an important risk factor?

Kamran Azma, Peyman Mottaghi, Alireza Hosseini, Shadi Salek, Roya Bina

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Advanced biomedical research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06549738 (Effects of Intermittent Pneumatic Compression Therapy on Tissue Volume, Pain, and Quality of Life in Women Living With Lipedema), which is not on this map. Cited by 3 papers.

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3citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06549738 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Intermittent Pneumatic Compression Therapy on Tissue Volume, Pain, and Quality of Life in Women Living With Lipedema

TypeinterventionalSponsorLympha PressRan2023 to 2023Enrolled46ConditionsLipedemaArmsIntermittent pneumatic compression therapy
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kamran AzmaDepartment of Physical Medicine and Rehabilitation, Clinical Biomechanical and Rehabilitation Engineering Research Center, AJA University of Medical Sciences, Tehran, Iran.
Peyman MottaghiDepartment of Internal medicine, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.
Alireza HosseiniDepartment of Orthopedic Surgery, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.
Shadi SalekDepartment of Pediatrics, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.
Roya BinaDepartment of Internal medicine, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.
Isfahan University of Medical Sciences · IRAja University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVaricose veins are extremely common disease which is due to elevated superficial venous pressures. We aimed to know that if joint hypermobility causes the venous insufficiency following the prolonged standing. MATERIALS AND

methodsThis prospective cohort study conducted on the soldiers of training periods in a military base of Iran Army in Isfahan in 2013. The active-duty soldiers were first examined by a physician and their Beighton scores (BSs) were obtained. At the onset of the training period, the presence of chronic venous insufficiency was clinically evaluated according to the C class of clinical, etiological, anatomical, and pathological classification. After 3 months, soldiers with and without joint hypermobility were reexamined for manifestations of venous insufficiency based on clinical examination.

resultsOf 718 soldiers, 211 subjects were diagnosed for joint hypermobility syndrome (29.3%). The mean BS was significantly higher in hypermobility soldiers (5.5 ± 1.5) than the healthy ones (1.2 ± 1.1). Before the training period, the prevalence of spider and varicose veins in soldiers with joint hypermobility was significantly higher than healthy subjects (P > 0.001). After the training period, the prevalence of venous insufficiency significantly increased in soldiers with joint hypermobility (P > 0.001) while there was no significant difference in healthy group before and after the period of training (P = 0.25).

conclusionHypermobility could be considered as a risk factor for the development of venous insufficiency, so it seems necessary to evaluate the population who need to be standing for a long time for evidence of joint hypermobility.

Indexed as

Joint hypermobilityprolonged standingvenous insufficiency

Identifiers

PMID26015924
PMCPMC4434442
OpenAlexW1605673304

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.