ReviewWorld journal of clinical pediatrics2015
Pyuria in patients with Kawasaki disease.
Review in World journal of clinical pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 41 citations in OpenAlex.
- Multisystem inflammatory syndrome in children and Kawasaki disease.Frontiers in immunology · 2025Review
- Diagnosis, Progress, and Treatment Update of Kawasaki Disease.International journal of molecular sciences · 2023Review
- Use of Machine Learning to Differentiate Children With Kawasaki Disease From Other Febrile Children in a Pediatric Emergency Department.JAMA network open · 2023Article
- Clinical Manifestations and Laboratory Findings of Kawasaki Disease: Beyond the Classic Diagnostic Features.Medicina (Kaunas, Lithuania) · 2022Review
- Angioma serpiginosum: Two cases in children and review of literature.Dermatology reports · 2022Article
- Sterile Pyuria in Kawasaki Disease: A Large Prospective Cohort Study.Frontiers in cardiovascular medicine · 2022Article
- Age-related differences in clinical characteristics of Kawasaki disease.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021Article
- From Skin to Kidneys: Cutaneous Clues of Renal Disease in Children.Dermatology practical & conceptual · 2020Review
- Unusual Presentation Of Kawasaki Disease With Gastrointestinal And Renal Manifestations.Therapeutics and clinical risk management · 2019Article
- Bacteriuria With CTX-M-8 Extended-Spectrum β-Lactamase-ProducingGlobal pediatric health · 2019Article
- Early features of Kawasaki disease with pyuria in febrile infants younger than 6 months.BMC pediatrics · 2018Article
- Antibody Profiling of Kawasaki Disease UsingMolecular & cellular proteomics : MCP · 2018Article
- Controversies in diagnosis and management of Kawasaki disease.World journal of clinical pediatrics · 2018Review
- Diagnosis of Kawasaki disease.International journal of rheumatic diseases · 2018Review
- The emergence of Kawasaki disease in India and China.Global cardiology science & practice · 2017Review
- Urinary Lactate Dehydrogenase Activity and Its Isozyme Patterns in Kawasaki Disease.International journal of pediatrics · 2017Article
- [Sterile leukocyturia - difficult diagnostic problem in children].Developmental period medicineReview
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Kawasaki disease (KD) is an acute, febrile vasculitis that predominantly develops in children ≤ 5 years of age and can lead to multiple organ injuries including the kidneys. Of these injuries, pyuria is a common feature of patients with KD, occurring in 30%-80% of patients. Sterile pyuria is most common in KD patients ≤ 1 year of age. KD patients with sterile pyuria exhibit more severe inflammatory reactions and may have sub-clinical renal injuries. Sterile pyuria in KD is associated with mononuclear cells (not neutrophils) in the urine. Although sterile pyuria in KD was at one time thought to be due to urethritis caused by a non-specific vasculitis of the urethra, recent studies suggest that sterile pyuria in KD originates from the urethra, the kidney as a result of mild and sub-clinical renal injuries, and/or the bladder due to cystitis. Pyuria is not always sterile in KD, but can result from a urinary tract infection (UTI). As causative pathogens, Escherichia coli and Klebsiella oxytoca have been reported. The clinical phenotypes do not differ between those with or without UTI. Because some KD patients with UTIs have urinary tract abnormalities such as vesicoureteral reflux, a complete UTI workup including renal ultrasound, voiding cystourethrogram and/or dimercaptosuccinic acid renal scan recommended in KD patients with UTIs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.