ArticleJournal of clinical medicine research2015
An Overlapping Case of Lupus Nephritis and IgG4-Related Kidney Disease.
Article in Journal of clinical medicine research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Urinary β2-microglobulin as a Potential Biomarker for Early Treatment Selection: A Patient with Severe IgG4-related Tubulointerstitial Nephritis.Internal medicine (Tokyo, Japan) · 2026Article
- Purpura as the initial manifestation of IgG4-related disease with concomitant systemic lupus erythematosus: a case report.Frontiers in medicine · 2026Article
- Discriminative features of immunoglobulin G4-related disease (IgG4-RD) and associated autoimmune rheumatic diseases (ARDs) in a nationwide observational cohort: study from the Egyptian College of Rheumatology.Clinical rheumatology · 2025Observational
- Case report and literature review: IgG4-related tubulointerstitial nephritis coexistent with systemic lupus erythematosus.Frontiers in medicine · 2025Article
- A unique case of IgG4-related skin disease and sclerosing cholangitis in a patient with previous hepatitis exposure.JAAD case reports · 2021Article
- An Overlapping Case of IgG4-related Disease and Klinefelter Syndrome with Lupus-like Serological and Neurological Features: A Case Report and Literature Review.Internal medicine (Tokyo, Japan) · 2020Article
- Pleomorphic Pulmonary Manifestations of IgG4-Related Disease.Case reports in rheumatology · 2019Article
- Perirenal capsule and scrotal involvement in immunoglobulin G4-related kidney disease: case-based review.Rheumatology international · 2018Review
- Overview of IgG4-Related Tubulointerstitial Nephritis and Its Mimickers.Journal of pathology and translational medicine · 2016Review
- An Overlapping Case of IgG4-Related Disease and Systemic Lupus Erythematosus.Journal of investigative medicine high impact case reportsArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
We report a case of a 71-year-old Filipino female who was admitted to the hospital for abdominal pain, vomiting and diarrhea of 8 days duration. The patient was found to have marked acute kidney injury (AKI), which required hemodialysis in the next 3 days. Extensive workup revealed hematuria, subnephrotic range proteinuria, elevated anti-nuclear antibody (ANA) and elevated total immunoglobulin G (IgG) levels, with normal IgG4 and anti-dsDNA levels. On kidney biopsy, mild membranous glomerulonephritis was found, along with autoimmune tubulointerstitial nephritis (TIN) with a "full-house" pattern of immune deposits. These findings were suggestive of lupus interstitial nephritis. However, IgG4+ plasma cells were detected in the interstitium by immunostaining, favoring a diagnosis of IgG4-related kidney disease (IgG4-RKD). Our case highlights the difficulty in differentiating lupus nephritis (LN) from IgG4-RKD in some patients, raising the suspicion that these two entities can co-exist.
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