Evidence map›Paper›PMID 26015818›Full record

ArticleJournal of clinical medicine research2015

Early prediction and outcome of septic encephalopathy in acute stroke patients with nosocomial coma.

Dao-Ming Tong, Ye-Ting Zhou, Guang-Sheng Wang, Xiao-Dong Chen, Tong-Hui Yang

Open access · diamondAbstract read
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Article in Journal of clinical medicine research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  3. Changes of rScOExperimental and therapeutic medicine · 2019
    Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Dao-Ming TongDepartment of Neurology, Affiliated Shuyang People's Hospital, XuZhou Medical College, Jiangsu, China ; Department of Neurology, the Affiliated Pingxiang Hospital, Southern Medical University, China ; These authors contributed equally to this work and shared first authorship.
Ye-Ting ZhouMedical Evaluation Unit, Affiliated Shuyang People's Hospital, XuZhou Medical College, Jiangsu, China ; These authors contributed equally to this work and shared first authorship.
Guang-Sheng WangDepartment of Neurology, Affiliated Shuyang People's Hospital, XuZhou Medical College, Jiangsu, China.
Xiao-Dong ChenDepartment of Neurology, Affiliated Shuyang People's Hospital, XuZhou Medical College, Jiangsu, China.
Tong-Hui YangDepartment of Neurology, Affiliated Shuyang People's Hospital, XuZhou Medical College, Jiangsu, China.
Xuzhou Medical College · CNAffiliated Hospital of Xuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeptic encephalopathy (SE) is the most common acute encephalopathy in ICU; however, little attention has been focused on risk of SE in the course of acute stroke. Our aim is to investigate the early prediction and outcome of SE in stroke patients with nosocomial coma (NC).

methodsA retrospective cohort study was conducted in an ICU of the tertiary teaching hospital in China from January 2006 to December 2009. Ninety-four acute stroke patients with NC were grouped according to with or without SE. Risk factors for patients with SE were compared with those without SE by univariate and multivariate analysis.

resultsOf 94 stroke patients with NC, 46 (49%) had NC with SE and 48 (51%) had NC without SE. The onset-to-NC time was significant later in stroke patients with SE than those without SE (P < 0.01). There was a significant difference in body temperature, heart rate, respiratory rate, white blood cell (WBC), systolic blood pressure (SBP), diastolic blood pressure (DBP), systemic inflammatory response syndrome (SIRS), acute respiratory failure, septic shock, hypernatremia, and sequential organ failure assessment (SOFA) score between the SE and non-SE group (P < 0.05). On a repeat head imaging, vasogenic edema (P = 0.023) and subcortical white matter lesions (P = 0.011) were significantly higher in patients with SE than those without SE, while hematoma growth (P = 0.000), infarction progress (P = 0.003), and recurrent subarachnoid hemorrhage (SAH) (P = 0.011) were significantly lower in patients with SE than those without SE. Patients with SE had higher adjusted rates of fever ≥ 39 °C (odds ratio (OR): 2.753; 95% confidence interval (CI): 1.116 - 6.794; P = 0.028) and SIRS ≥ 3 items (OR: 6.459; 95% CI: 2.050 - 20.351; P = 0.001). The 30-day mortality in stroke patients with SE was higher than those without SE (76.1% vs. 45.8%, P = 0.003).

conclusionHigh fever and severe SIRS are two early predictors of stroke patients with SE, and survival rates were worse in stroke patients with SE than those without SE.

Indexed as

InfectionNosocomial comaOutcomeSeptic encephalopathyStrokeSystemic inflammatory response syndrome

Identifiers

PMID26015818
PMCPMC4432895
OpenAlexW1604798999

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.