Evidence map›Paper›PMID 26015789›Full record

ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

Public health response to a large-scale endoscopy infection control lapse in a nonhospital clinic.

Jacqueline Willmore, Edward Ellis, Vera Etches, Lise Labrecque, Carla Osiowy, Anton Andonov, Cameron McDermaid, Anna Majury, Camille Achonu, Maurica Maher and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Infection prevention and control lapse involving medical equipment reprocessing at a family medicine clinic in Ottawa, Ontario, 2018.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2020
    Article
  4. Public health investigation of infection prevention and control complaints in Ontario, 2015-2018.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jacqueline WillmoreOttawa Public Health;
Edward EllisPublic Health and Preventive Medicine Consultant; ; University of Ottawa, Ottawa, Ontario;
Vera EtchesOttawa Public Health; ; University of Ottawa, Ottawa, Ontario;
Lise LabrecqueOttawa Public Health;
Carla OsiowyNational Microbiology Laboratory, Public Health Agency of Canada; ; University of Manitoba, Winnipeg, Manitoba;
Anton AndonovNational Microbiology Laboratory, Public Health Agency of Canada; ; University of Manitoba, Winnipeg, Manitoba;
Cameron McDermaidOttawa Public Health;
Anna MajuryPublic Health Ontario; ; Queen's University, Kingston;
Camille AchonuPublic Health Ontario, Toronto;
Maurica MaherHealth Canada, Ottawa, Ontario.
Brenda MacLeanOttawa Public Health;
Isra LevyOttawa Public Health;

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine whether transmission of blood-borne pathogens (BBPs) (hepatitis B virus [HBV], hepatitis C virus [HCV] and HIV) occurred as a result of endoscopy reprocessing failures identified during an inspection of a nonhospital endoscopy clinic in 2011.

methodsThe present analysis was a retrospective cohort study. Registered notification letters were mailed to 6992 patients who underwent endoscopy from 2002 to 2011 at one Canadian nonhospital endoscopy clinic, informing them of the infection control lapse and offering BBP testing. Multimedia communications and a telephone line supplemented notification. A retrospective study of patients with BBPs was performed with viral genetic testing and risk factor assessment for eligible patients. Risk for infection among patients whose procedure was within seven days of a known positive patient was compared with those whose procedure was performed more than seven days after a known postive patient. The seven-day period was selected as the period most likely to present a risk for transmission based on the documented cleaning procedures at the clinic and the available literature on virus survival.

resultsNinety-five percent (6628 of 6992) of patients/estates were contacted and 5042 of 6728 (75%) living patients completed BBP testing. Three were newly diagnosed with HBV and 14 with HCV. Twenty-three and 48 tested positive for previously known HBV or HCV, respectively, 367 were immune to HBV due to natural infection and one was immune to HBV due to immunization. None tested positive for HIV. Sequencing did not reveal any relationships among the 46 unique case patients with viral genetic test results available. Ninety-three percent of patients reported alternative risk factors for BBP. An increased risk for infection among those who underwent a procedure within seven days of a known HBV or HCV case was not demonstrated.

conclusionsEndoscopy reprocessing failures were not associated with an increased risk for BBP among individuals tested.

Indexed as

EndoscopyInfection control lapsePublic health

Identifiers

PMID26015789
PMCPMC4419818

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.