Observational studyThe American journal of tropical medicine and hygiene2015
Prospective cohort study with active surveillance for fever in four dengue endemic countries in Latin America.
Observational study in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01293331 (Prospective Surveillance of Febrile Illness for Dengue-Endemic Areas in Latin America), which is not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective Surveillance of Febrile Illness for Dengue-Endemic Areas in Latin America
Who cites it
16 citing papers in PubMed.
- Safety and Immunogenicity of an AS03The American journal of tropical medicine and hygiene · 2020Trial
- Secondary Analysis of the Efficacy and Safety Trial Data of the Tetravalent Dengue Vaccine in Children and Adolescents in Colombia.The Pediatric infectious disease journal · 2020Trial
- Periods of high dengue transmission defined by rainfall do not impact efficacy of dengue vaccine in regions of endemic disease.PloS one · 2018Trial
- Dengue Fever Epidemics and the Prospect of Vaccines: A Systematic Review and Meta-Analysis Using Clinical Trials in Children.Diseases (Basel, Switzerland) · 2024Review
- Incidence of lab-confirmed dengue fever in a pediatric cohort in Delhi, India.PLoS neglected tropical diseases · 2022Article
- Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil.BMC infectious diseases · 2020Article
- Dengue Infection in Children in Fortaleza, Brazil: A 3-Year School-Based Prospective Cohort Study.The American journal of tropical medicine and hygiene · 2020Article
- Dengue: 30 years of cases in an endemic area.Clinics (Sao Paulo, Brazil) · 2019Review
- Factors Associated with Dengue Virus Infection and Reinfection in Asymptomatic Children in Two Colombian Municipalities.The American journal of tropical medicine and hygiene · 2018Article
- Estimating dengue incidence and hospitalization in Malaysia, 2001 to 2013.BMC public health · 2018Article
- Long-term epidemiological dynamics of dengue in Barbados - one of the English-speaking Caribbean countries.Epidemiology and infection · 2018Article
- Contributions from the silent majority dominate dengue virus transmission.PLoS pathogens · 2018Article
- The use of longitudinal cohorts for studies of dengue viral pathogenesis and protection.Current opinion in virology · 2018Review
- Risk Factors Associated with Dengue Transmission and Spatial Distribution of High Seroprevalence in Schoolchildren from the Urban Area of Medellin, Colombia.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2018Article
- Clinical and epidemiologic characteristics of dengue and other etiologic agents among patients with acute febrile illness, Puerto Rico, 2012-2015.PLoS neglected tropical diseases · 2017Article
- Immune status alters the probability of apparent illness due to dengue virus infection: Evidence from a pooled analysis across multiple cohort and cluster studies.PLoS neglected tropical diseases · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To prepare for a Phase III dengue vaccine efficacy trial, 20 investigational sites were selected for this observational study to identify dengue infections in a closed cohort (N = 3,000 children 9-16 years of age). Of 255 acute febrile episodes experienced by 235 children, 50 (21.3%) were considered serologically probable dengue, and 18 (7.7%) were considered virologically confirmed (i.e., dengue NS1 antigen positive) dengue cases. Considering the disease-free and at-risk period from study start to onset of symptoms, the overall incidence density of acute febrile episodes was 17.7 per 100 person-years of follow-up, ranging from 15.3 in Colombia to 22.0 in Puerto Rico. This study showed that all sites were capable of capturing and following up acute febrile episodes within a specific timeframe among the established cohort and to detect dengue cases.
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Registered trials
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