Evidence map›Paper›PMID 26012476›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2015

Arterial hypotension and prerenal failure in an extremely preterm infant associated with oral sildenafil.

H Balasubramanian, T Strunk, R Kohan

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Sildenafil Exposure in the Neonatal Intensive Care Unit.American journal of perinatology · 2019
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

H BalasubramanianNeonatal Clinical Care Unit, King Edward Memorial Hospital for Women, Perth, WA, Australia.
T Strunk1] Neonatal Clinical Care Unit, King Edward Memorial Hospital for Women, Perth, WA, Australia [2] Centre for Neonatal Research and Education, School of Paediatrics and Child Health University of Western Australia, Perth, WA, Australia.
R Kohan1] Neonatal Clinical Care Unit, King Edward Memorial Hospital for Women, Perth, WA, Australia [2] Centre for Neonatal Research and Education, School of Paediatrics and Child Health University of Western Australia, Perth, WA, Australia.
King Edward Memorial Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report significant hypotension and prerenal failure in an extremely preterm infant following two doses of oral sildenafil that warranted discontinuation of the drug and treatment with inotropes. Blood pressure and urine output normalized after 24 h of withdrawal of the oral drug. Sildenafil should be used cautiously in extremely preterm infants early in the neonatal course, where there is limited data on its efficacy and safety.

Indexed as

Infant, Extremely PrematureAcidosis, LacticAdministration, OralFemaleHumansHypotensionInfant, NewbornKidneyPersistent Fetal Circulation SyndromeSildenafil CitrateVasodilator AgentsSildenafil CitrateVasodilator Agents

Identifiers

PMID26012476
OpenAlexW1592731154

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.