Evidence map›Paper›PMID 26011508›Full record

Trial reportAddiction (Abingdon, England)2015

Can cannabis use be prevented by targeting personality risk in schools? Twenty-four-month outcome of the adventure trial on cannabis use: a cluster-randomized controlled trial.

Ioan T Mahu, Christine Doucet, Maeve O'Leary-Barrett, Patricia J Conrod

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Addiction (Abingdon, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05383989 (UniVenture), which is not on this map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05383989 naunknown statusnot on this mapstarted 2021, after this paper: background citation

UniVenture: A Partnership to Address Heavy Drinking and Other Substance Misuse on Canadian University Campuses

TypeinterventionalSponsorSherry StewartRan2021 to 2024Enrolled1,000ConditionsAnxiety Sensitivity, Hopelessness, Sensation Seeking, ImpulsivityArmsUniVenture Hopelessness manual, UniVenture Anxiety Sensitivity manual, UniVenture Sensation Seeking manual, UniVenture Impulsivity manual, Service as usual provided by the University
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  15. Classical and Neural Network Machine Learning to Determine the Risk of Marijuana Use.International journal of environmental research and public health · 2021
    Article
  16. Which came first: Cannabis use or deficits in impulse control?Progress in neuro-psychopharmacology & biological psychiatry · 2021
    Review
  17. Article
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  20. Impulsivities and addictions: a multidimensional integrative framework informing assessment and interventions for substance use disorders.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Ioan T MahuUniversité de Montréal, Centre Hospitalier et Universitaire Ste-Justine, Department of Psychiatry, Montréal, Canada.ORCID http://orcid.org/0000-0001-9606-7864
Christine DoucetUniversité de Montréal, Centre Hospitalier et Universitaire Ste-Justine, Department of Psychiatry, Montréal, Canada.
Maeve O'Leary-BarrettMcGill University, Montréal, Canada.
Patricia J ConrodUniversité de Montréal, Centre Hospitalier et Universitaire Ste-Justine, Department of Psychiatry, Montréal, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo examine the effectiveness of a personality-targeted intervention program (Adventure trial) delivered by trained teachers to high-risk (HR) high-school students on reducing marijuana use and frequency of use.

designA cluster-randomized controlled trial.

settingSecondary schools in London, UK.

participantsTwenty-one secondary schools were randomized to intervention (n = 12) or control (n = 9) conditions, encompassing a total of 1038 HR students in the ninth grade [mean (standard deviation) age = 13.7 (0.33) years].

interventionsBrief personality-targeted interventions to students with one of four HR profiles: anxiety sensitivity, hopelessness, impulsivity and sensation-seeking. MEASUREMENTS: PRIMARY OUTCOME: marijuana use. Secondary outcome: frequency of use. Assessed using the Reckless Behaviour Questionnaire at intervals of 6 months for 2 years. Personality risk was measured with the Substance Use Risk Profile Scale.

findingsLogistic regression analysis revealed significant intervention effects on cannabis use rates at the 6-month follow-up in the intent-to-treat sample [odds ratio (OR) = 0.67, P = 0.05, 95% confidence interval (CI) = 0.45-1.0] and significant reductions in frequency of use at 12- and 18-month follow-up (β = -0.14, P ≤ 0.05, 95% CI = -0.6 to -0.01; β = -0.12, P ≤ 0.05, 95% CI = -0.54 to 0.0), but this was not supported in two-part latent growth models. Subgroup analyses (both logistic and two-part models) reveal that the sensation-seeking intervention delayed the onset of cannabis use among sensation seekers (OR = 0.25, β = -0.833, standard error = 0.342, P = 0.015).

conclusionsPersonality-targeted interventions can be delivered effectively by trained school staff to delay marijuana use onset among a subset of high-risk teenagers: sensation-seekers.

Indexed as

PersonalityAdolescentAnxietyCognitive Behavioral TherapyFemaleHopeHumansImpulsive BehaviorLinear ModelsLogistic ModelsLondonMaleMarijuana SmokingMotivational InterviewingPatient Education as TopicRisk AssessmentAdolescentsdrug preventionimpulsivitypersonalitysensation seekingtargeted prevention

Identifiers

PMID26011508
PMCPMC5034824

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.