Evidence map›Paper›PMID 26010909›Full record

ReviewJAMA neurology2015

Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder.

Stephane Kremer, Felix Renard, Sophie Achard, Marco A Lana-Peixoto, Jacqueline Palace, Nasrin Asgari, Eric C Klawiter, Silvia N Tenembaum, Brenda Banwell, Benjamin M Greenberg and 39 more

Open access · bronzeAbstract readReview
In one paragraph

Review in JAMA neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Advanced MRI quantification of neuroinflammatory disorders.Journal of neuroscience research · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. MRI characteristics of Japanese macaque encephalomyelitis: Comparison to human diseases.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2021
    Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Observational
  17. Quantitative 7T MRI does not detect occult brain damage in neuromyelitis optica.Neurology(R) neuroimmunology & neuroinflammation · 2019
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

49 authors at 20 institutions in 17 countries.

Stephane KremerICube (UMR 7357, UdS, Centre National de la Recherche Scientifique), Fédération de médecine translationelle de Strasbourg, Université de Strasbourg, Strasbourg, France2Department of Radiology, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Felix RenardCentre National de la Recherche Scientifique, Grenoble Image Parole Signal Automatique, Grenoble, France.
Sophie AchardCentre National de la Recherche Scientifique, Grenoble Image Parole Signal Automatique, Grenoble, France.
Marco A Lana-PeixotoCIEM MS Research Center, University of Minas Gerais, Minas Gerais, Brazil.
Jacqueline PalaceDepartment of Neurology, Oxford University Hospital Trust, Oxford, England.
Nasrin AsgariDepartment of Neurobiology, Institute of Molecular Medicine, University of Southern Denmark, Odense7Department of Neurology, Vejle Hospital, Vejle, Denmark.
Eric C KlawiterDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston.
Silvia N TenembaumDepartment of Neurology and Neurophysiology, National Pediatric Hospital Dr Juan P. Garrahan, Buenos Aires, Argentina.
Brenda BanwellDepartment of Neurology, University of Pennsylvania, Philadelphia11Division of Child Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Benjamin M GreenbergDepartment of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas13Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas.
Jeffrey L BennettDepartment of Neurology, University of Colorado Denver, Aurora15Department of Ophthalmology, University of Colorado Denver, Aurora.
Michael LevyDepartment of Neurology, Johns Hopkins University, Baltimore, Maryland.
Pablo VillosladaInstitute of Biomedical Research August Pi Sunyer-Hospital Clínic de Barcelona, Barcelona, Spain.
Albert SaizInstitute of Biomedical Research August Pi Sunyer-Hospital Clínic de Barcelona, Barcelona, Spain.
Kazuo FujiharaDepartment of Multiple Sclerosis Therapeutics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Koon Ho ChanUniversity Department of Medicine, Research Center of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, People's Republic of China.
Sven SchipplingNeuroimmunology and Multiple Sclerosis Research Section, University Hospital Zurich, Zurich, Switzerland21Department of Neurology, University Hospital Zurich, Zurich, Switzerland22Neuroscience Center Zurich, Federal Technical High School Zurich, Zurich, S.
Friedemann PaulNeuroCure Clinical Research Center, Charité University Medicine, Berlin, Germany25Clinical and Experimental Multiple Sclerosis Research Center, Charité University Medicine, Berlin, Germany26Department of Neurology, Charité University Medicine, Berlin, Ger.
Ho Jin KimDepartment of Neurology, Research Institute, Goyang, Korea28Hospital of National Cancer Center, Goyang, Korea.
Jerome de SezeNeurology Department, Hôpitaux Universitaires de Strasbourg, Strasbourg, France30Clinical Investigation Center (INSERM 1434), Hôpitaux Universitaires de Strasbourg, Strasbourg, France31UMR INSERM 1119 and Fédération de médecine translationelle, Strasbourg.
Jens T WuerfelNeuroCure Clinical Research Center, Charité University Medicine, Berlin, Germany25Clinical and Experimental Multiple Sclerosis Research Center, Charité University Medicine, Berlin, Germany26Department of Neurology, Charité University Medicine, Berlin, Ger.
Guthy-Jackson Charitable Foundation (GJCF) Neuromyelitis Optica (NMO) International Clinical Consortium and Biorepository
Philippe CabreCHU de Fort de France, Martinique.
Romain MarignierCHU, Lyon, France.
Thomas TedderDuke University School of Medicine, Durham, North Carolina.
Danielle van PeltErasmus MC, Rotterdam, the Netherlands.
Simon BroadleyGriffith University, Southport, Queensland, Australia.
Tanuja ChitnisDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston.
Dean WingerchukMayo Clinic, Scottsdale, Arizona.
Lekha PanditNitte University, Mangalore, Karnataka, India.
Maria Isabel LeiteDepartment of Neurology, Oxford University Hospital Trust, Oxford, England.
Metha ApiwattanakulPrasat Neurological Institute, Bangkok, Thailand.
Ingo KleiterRuhr University, Bochum, Germany.
Naraporn PrayoonwiwatSiriraj Hospital, Mahidol University, Bangkok, Thailand.
May HanStanford University School of Medicine, Palo Alto, California.
Kerstin HellwigSt Josef Hospital, Bochum, Germany.
Katja van HerleThe GJCF, San Diego, California.
Gareth JohnMount Sinai Hospital, New York, New York.
D Craig HooperThomas Jefferson University, Philadelphia, Pennsylvania.
Ichiro NakashimaDepartment of Multiple Sclerosis Therapeutics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Douglas SatoDepartment of Multiple Sclerosis Therapeutics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Michael R YeamanUniversity of California, Los Angeles.
Emmanuelle WaubantUniversity of California, San Francisco.
Scott ZamvilUniversity of California, San Francisco.
Olaf StüveDepartment of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas13Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas.
Orhan AktasUniversity of Düsseldorf, Düsseldorf, Germany.
Terry J SmithUniversity of Michigan, Ann Arbor.
Anu JacobWalton Center, Liverpool, England.
Kevin O'ConnorYale University School of Medicine, New Haven, Connecticut.
Tohoku University · JPCharité - Universitätsmedizin Berlin · DEHarvard University · USHôpitaux Universitaires de Strasbourg · FRHospital Clínic de Barcelona · ESOxford University Hospitals NHS Trust · GBThe University of Texas Southwestern Medical Center · USUniversity of California, San Francisco · USCentre Hospitalier Universitaire de Martinique · MQCentre National de la Recherche Scientifique · FRDuke University · USErasmus MC · NLGarrahan Hospital · ARGranulosa Cell Tumor of the Ovary Foundation · USGrenoble Images Parole Signal Automatique · FRGriffith University · AUHeinrich Heine University Düsseldorf · DEJohns Hopkins University · USMahidol University · THMayo Clinic in Arizona · US

Funding

Humoral Immunity, Astrocyte Injury, and Demyelination in Neuromyelitis OpticaR01EY022936 · NEI · UNIVERSITY OF COLORADO DENVER · PI BENNETT, JEFFREY L · 2013 to 2022
$3.8M
immunopathogenesis of NMO-IgG and AQP4-specific T cells in neuromyelitis opticaK08NS078555 · NINDS · JOHNS HOPKINS UNIVERSITY · PI LEVY, MICHAEL · 2013 to 2017
$965k
NEI NIH HHS R01 EY022936NINDS NIH HHS K08 NS078555
6 · The paper itself

Abstract

Brain parenchymal lesions are frequently observed on conventional magnetic resonance imaging (MRI) scans of patients with neuromyelitis optica (NMO) spectrum disorder, but the specific morphological and temporal patterns distinguishing them unequivocally from lesions caused by other disorders have not been identified. This literature review summarizes the literature on advanced quantitative imaging measures reported for patients with NMO spectrum disorder, including proton MR spectroscopy, diffusion tensor imaging, magnetization transfer imaging, quantitative MR volumetry, and ultrahigh-field strength MRI. It was undertaken to consider the advanced MRI techniques used for patients with NMO by different specialists in the field. Although quantitative measures such as proton MR spectroscopy or magnetization transfer imaging have not reproducibly revealed diffuse brain injury, preliminary data from diffusion-weighted imaging and brain tissue volumetry indicate greater white matter than gray matter degradation. These findings could be confirmed by ultrahigh-field MRI. The use of nonconventional MRI techniques may further our understanding of the pathogenic processes in NMO spectrum disorders and may help us identify the distinct radiographic features corresponding to specific phenotypic manifestations of this disease.

Indexed as

Clinical Trials as TopicDiffusion Tensor ImagingHumansMagnetic Resonance ImagingNeuromyelitis Optica

Identifiers

PMID26010909
PMCPMC4828237
OpenAlexW1699765682

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.