ArticlePloS one2015
Non-Linear Association between Exposure to Ambient Temperature and Children's Hand-Foot-and-Mouth Disease in Beijing, China.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The effect of daily mean temperature on hand, foot and mouth disease and the source of regional heterogeneity in Chongqing, China, 2010-2019.Environmental health and preventive medicine · 2022Pooled it
- Association of Short-Term Exposure to Meteorological Factors and Risk of Hand, Foot, and Mouth Disease: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- Temporal relationships between climate variables and hand-foot-mouth disease: a multi-province study in the Mekong Delta Region, Vietnam.International journal of biometeorology · 2020Pooled it
- Short-term effects of meteorological factors on hand, foot, and mouth disease in Zhengzhou, China.Scientific reports · 2026Article
- The impact of anthropogenic climate change on pediatric viral diseases.Pediatric research · 2024Review
- Non-linear association between daily mean temperature and children's hand foot and mouth disease in Chongqing, China.Scientific reports · 2023Article
- Combined impacts of environmental and socioeconomic covariates on HFMD risk in China: A spatiotemporal heterogeneous perspective.PLoS neglected tropical diseases · 2023Article
- Impact of meteorological factors on the incidence of hand-foot-mouth disease in Yangzhou from 2017 to 2022: a time series study.Frontiers in public health · 2023Article
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- Effects of Meteorological Factors and Atmospheric Pollution on Hand, Foot, and Mouth Disease in Urumqi Region.Frontiers in public health · 2022Article
- Association between Meteorological Parameters and Hand, Foot and Mouth Disease in Mainland China: A Systematic Review and Meta-Analysis.Iranian journal of public health · 2021Review
- Non-linear effect of different humidity types on scrub typhus occurrence in endemic provinces, Thailand.Heliyon · 2021Article
- Assessment of Temperature-Hand, Foot, and Mouth Disease Association and Its Variability across Urban and Rural Populations in Wuxi, China: A Distributed Lag Nonlinear Analysis.The American journal of tropical medicine and hygiene · 2020Article
- Short-term effects of meteorological factors, air pollution, and sunspot on childhood hand, foot, and mouth disease in Tianjin, China: a new time series regression, 2014-2018.Environmental science and pollution research international · 2020Article
- Climate factors driven typhus group rickettsiosis incidence dynamics in Xishuangbanna Dai autonomous prefecture of Yunnan province in China, 2005-2017.Environmental health : a global access science source · 2020Article
- A method for hand-foot-mouth disease prediction using GeoDetector and LSTM model in Guangxi, China.Scientific reports · 2019Article
- The effect of temperature on childhood hand, foot and mouth disease in Guangdong Province, China, 2010-2013: a multicity study.BMC infectious diseases · 2019Article
- Spatial-temporal variation and risk factor analysis of hand, foot, and mouth disease in children under 5 years old in Guangxi, China.BMC public health · 2019Article
- Analysis of the effect of PM10 on hand, foot and mouth disease in a basin terrain city.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHand, foot and mouth disease (HFMD) was listed as a notifiable communicable disease in 2008 and is an emerging public health problem in China, especially for children. However, few data are available on the risk assessment of the potential reasons for HFMD in Beijing. This study examined the association of temperature with the incidence of children's HFMD in Beijing at the daily scale for the first time.
methodsA newly developed case-crossover design with a distributed lag nonlinear model (DLNM) was used to assess the delayed and cumulative associations of daily temperature with gender- and age-specific HFMD in Beijing, China, during 2010-2012. Relative humidity, day of the week, public holiday, season and long-term trends were controlled in the model.
resultsAmong the total of 113,475 cases, the ratio between males and females was 1.52:1. HFMD was more prevalent in May-July. The temperature-HFMD relationships were non-linear in most age groups except for children aged 6-15 years, with a peak at 25.0~27.5°C. The high-temperature risks were greater, appeared earlier and lasted longer than the low-temperature risks. The relative risks for female children and those aged 6-15 years were higher than those among other groups.
conclusionRising temperatures increased the incidence of children's HFMD, with the largest association at 25.0~27.5°C. Females and children aged 6-15 years were more vulnerable to changes in temperature with regard to the transmission of HFMD than males and other age groups, respectively. Further studies are warranted to confirm these findings in other populations.
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