Evidence map›Paper›PMID 26009974›Full record

ReviewCell proliferation2015

Review of natural product databases.

Tao Xie, Sicheng Song, Sijia Li, Liang Ouyang, Lin Xia, Jian Huang

Abstract readReview
In one paragraph

Review in Cell proliferation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
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  4. Article
  5. Article
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  7. Review
  8. Article
  9. Review
  10. Cheminformatics-Based Study Identifies Potential Ebola VP40 Inhibitors.International journal of molecular sciences · 2023
    Article
  11. New approaches in developing medicinal herbs databases.Database : the journal of biological databases and curation · 2023
    Review
  12. Review
  13. Molecular Mechanisms ofCombinatorial chemistry & high throughput screening · 2023
    Article
  14. An Overview onEvidence-based complementary and alternative medicine : eCAM · 2022
    Review
  15. Review
  16. Review
  17. Article
  18. Semisynthesis of Selenoauraptene.Molecules (Basel, Switzerland) · 2021
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tao XieState Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.
Sicheng SongState Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.
Sijia LiState Key Laboratory of Stomatology, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.
Liang OuyangState Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China.
Lin XiaDepartment of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China.
Jian HuangSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMany natural products have pharmacological or biological activities that can be of therapeutic benefit in treating diseases, and are also an important source of inspiration for development of potential novel drugs. The past few decades have witnessed extensive study of natural products for their promising prospects in application of medicinal chemistry, molecular biology and pharmaceutical sciences. MATERIALS AND

methodsNatural product databases have provided systematic collection of information concerning natural products and their derivatives, including structure, source and mechanisms of action, which significantly support modern drug discovery.

resultsCurrently, a considerable number of natural product databases, such as TCM Database@Taiwan, TCMID, CEMTDD, SuperToxic and SuperNatural, have been developed, providing data such as integrated medicinal herbs, ingredients, 2D/3D structures of the compounds, related target proteins, relevant diseases, and metabolic toxicity and more.

conclusionsWe focus on an analytical overview of current natural product databases, and further discuss the good, bad or imperfection of current ones, in the hope of better integrating existing relevant outcomes, thus providing new routes for future drug discovery.

Indexed as

Databases, FactualDrug DiscoveryAnimalsBiological ProductsDrugs, Chinese HerbalHumansBiological ProductsDrugs, Chinese Herbal

Identifiers

PMID26009974
PMCPMC6495245

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.