ArticleThe American journal on addictions2015
"Sub is a weird drug:" A web-based study of lay attitudes about use of buprenorphine to self-treat opioid withdrawal symptoms.
Article in The American journal on addictions, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Linguistic Markers of Pain Communication on X (Formerly Twitter) in US States With High and Low Opioid Mortality: Machine Learning and Semantic Network Analysis.Journal of medical Internet research · 2025Article
- An Analysis of the Prevalence and Trends in Drug-Related Lyrics on Twitter (X): Quantitative Approach.JMIR formative research · 2024Article
- Trajectories of non-prescribed buprenorphine and other opioid use: A multi-trajectory latent class growth analysis.Journal of substance use and addiction treatment · 2023Article
- Scope of, Motivations for, and Outcomes Associated with Buprenorphine Diversion in the United States: A Scoping Review.Substance use & misuse · 2023Article
- Drug Abuse Ontology to Harness Web-Based Data for Substance Use Epidemiology Research: Ontology Development Study.JMIR public health and surveillance · 2022Article
- Listed for sale: Analyzing data on fentanyl, fentanyl analogs and other novel synthetic opioids on one cryptomarket.Drug and alcohol dependence · 2020Article
- Mining Social Media Data for Biomedical Signals and Health-Related Behavior.Annual review of biomedical data science · 2020Article
- Characterization of diverted buprenorphine use among adults entering corrections-based drug treatment in Kentucky.Drug and alcohol dependence · 2020Article
- Case report: Successful induction of buprenorphine/naloxone using a microdosing schedule and assertive outreach.Addiction science & clinical practice · 2020Article
- Buprenorphine/naloxone induction for treatment of acute on chronic pain using a micro-dosing regimen: A case report.Canadian journal of pain = Revue canadienne de la douleur · 2019Article
- Pharmacologic Treatment of Opioid Use Disorder: a Review of Pharmacotherapy, Adjuncts, and Toxicity.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2018Review
- Scaling Up Research on Drug Abuse and Addiction Through Social Media Big Data.Journal of medical Internet research · 2017Article
- Increases in synthetic cannabinoids-related harms: Results from a longitudinal web-based content analysis.The International journal on drug policy · 2017Article
- Using Social Listening Data to Monitor Misuse and Nonmedical Use of Bupropion: A Content Analysis.JMIR public health and surveillance · 2017Article
- "When 'Bad' is 'Good'": Identifying Personal Communication and Sentiment in Drug-Related Tweets.JMIR public health and surveillance · 2016Article
- Should the United States Government Repeal Restrictions on Buprenorphine/Naloxone Treatment?Substance use & misuse · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIllicit use of buprenorphine has increased in the U.S., but our understanding of its use remains limited. This study aims to explore Web-forum discussions about the use of buprenorphine to self-treat opioid withdrawal symptoms.
methodsPREDOSE, a novel Semantic Web platform, was used to extract relevant posts from a Web-forum that allows free discussions on illicit drugs. First, we extract information about the total number of buprenorphine-related posts per year between 2005 and 2013. Second, PREDOSE was used to identify all posts that potentially contained discussions about buprenorphine and opioid withdrawal. A total number of 1,217 posts that contained these terms were extracted and entered into NVivo data base. A random sample of 404 (33%) posts was selected and content analyzed.
resultsBuprenorphine-related posts increased over time, peaking in 2011. The posts were about equally divided between those that expressed positive and negative views about the effectiveness of buprenorphine in relieving withdrawal symptoms. Web-forum participants emphasized that buprenorphine's effectiveness may become compromised because of the "size of a person habit," and/or when users repeatedly switch back and forth between buprenorphine and other illicit opioids. Most posts reported use of significantly lower amounts of buprenorphine (≤2 mg) than doses used in standard treatment. Concomitant use of other psychoactive substances was also commonly reported, which may present significant health risks.
conclusionsOur findings highlight the usefulness of Web-based data in drug abuse research and add new information about lay beliefs about buprenorphine that may help inform prevention and policy measures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.