Evidence map›Paper›PMID 26008876›Full record

ArticleInfection control and hospital epidemiology2015

Seasonal Variation of Common Surgical Site Infections: Does Season Matter?

Michael J Durkin, Kristen V Dicks, Arthur W Baker, Sarah S Lewis, Rebekah W Moehring, Luke F Chen, Daniel J Sexton, Deverick J Anderson

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Infection control and hospital epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04299737 (Improving Case Selection for Perioperative S. Aureus Transmission Surveillance to Reduce Surgical Site Infections), which is not on this map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04299737 withdrawnnot on this mapstarted 2020, after this paper: background citation

Improving Case Selection for Perioperative S. Aureus Transmission Surveillance to Reduce Surgical Site Infections

TypeobservationalSponsorRandy LoftusRan2020 to 2021Enrolled0ConditionsS. Aureus TransmissionArmsTreatment Bundle (as defined below)
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

  1. Association between extreme weather events and postoperative adverse outcomes: a systematic review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025
    Pooled it
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  13. [Climate change and (surgical) health in context].Chirurgie (Heidelberg, Germany) · 2023
    Review
  14. How Antimicrobial Resistance Is Linked to Climate Change: An Overview of Two Intertwined Global Challenges.International journal of environmental research and public health · 2023
    Review
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Michael J Durkin1Division of Infectious Diseases,Department of Medicine,Duke University Medical Center,Durham,North Carolina.
Kristen V Dicks1Division of Infectious Diseases,Department of Medicine,Duke University Medical Center,Durham,North Carolina.
Arthur W Baker1Division of Infectious Diseases,Department of Medicine,Duke University Medical Center,Durham,North Carolina.
Sarah S Lewis1Division of Infectious Diseases,Department of Medicine,Duke University Medical Center,Durham,North Carolina.
Rebekah W Moehring1Division of Infectious Diseases,Department of Medicine,Duke University Medical Center,Durham,North Carolina.
Luke F Chen1Division of Infectious Diseases,Department of Medicine,Duke University Medical Center,Durham,North Carolina.
Daniel J Sexton1Division of Infectious Diseases,Department of Medicine,Duke University Medical Center,Durham,North Carolina.
Deverick J Anderson1Division of Infectious Diseases,Department of Medicine,Duke University Medical Center,Durham,North Carolina.
Duke Medical Center · USDurham VA Medical Center · US

Funding

Defining Measures of Impact for Antimicrobial Stewardship Programs in Community HospitalsK08HS023866 · AHRQ · DUKE UNIVERSITY · PI MOEHRING, REBEKAH WHITE · 2015 to 2019
$739k
Clinical and Molecular Epidemiology of Multidrug-Resistant Organisms in a CommuniK23AI095357 · NIAID · DUKE UNIVERSITY · PI ANDERSON, DEVERICK JOHN · 2011 to 2015
$644k
AHRQ HHS K08 HS023866NIAID NIH HHS K23 AI095357
6 · The paper itself

Abstract

objectiveTo evaluate seasonal variation in the rate of surgical site infections (SSI) following commonly performed surgical procedures.

designRetrospective cohort study.

methodsWe analyzed 6 years (January 1, 2007, through December 31, 2012) of data from the 15 most commonly performed procedures in 20 hospitals in the Duke Infection Control Outreach Network. We defined summer as July through September. First, we performed 3 separate Poisson regression analyses (unadjusted, multivariable, and polynomial) to estimate prevalence rates and prevalence rate ratios of SSI following procedures performed in summer versus nonsummer months. Then, we stratified our results to obtain estimates based on procedure type and organism type. Finally, we performed a sensitivity analysis to test the robustness of our findings.

resultsWe identified 4,543 SSI following 441,428 surgical procedures (overall prevalence rate, 1.03/100 procedures). The rate of SSI was significantly higher during the summer compared with the remainder of the year (1.11/100 procedures vs 1.00/100 procedures; prevalence rate ratio, 1.11 [95% CI, 1.04-1.19]; P=.002). Stratum-specific SSI calculations revealed higher SSI rates during the summer for both spinal (P=.03) and nonspinal (P=.004) procedures and revealed higher rates during the summer for SSI due to either gram-positive cocci (P=.006) or gram-negative bacilli (P=.004). Multivariable regression analysis and sensitivity analyses confirmed our findings.

conclusionsThe rate of SSI following commonly performed surgical procedures was higher during the summer compared with the remainder of the year. Summer SSI rates remained elevated after stratification by organism and spinal versus nonspinal surgery, and rates did not change after controlling for other known SSI risk factors.

Indexed as

BacillusGram-Positive CocciSeasonsGram-Negative Bacterial InfectionsGram-Positive Bacterial InfectionsHumansPrevalenceRetrospective StudiesSoutheastern United StatesSpineSurgical Wound Infection

Identifiers

PMID26008876
PMCPMC4748703
OpenAlexW376203845

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.