ArticleAmerican journal of perinatology2015
Skin-to-Skin Care and the Development of the Preterm Infant Oral Microbiome.
Article in American journal of perinatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed.
- Oral colostrum priming shortens hospitalization without changing the immunomicrobial milieu.Journal of perinatology : official journal of the California Perinatal Association · 2017Trial
- Buccal administration of human colostrum: impact on the oral microbiota of premature infants.Journal of perinatology : official journal of the California Perinatal Association · 2016Trial
- From early prevention to invasive treatment: dental care utilization and outcomes according to gestational age in preterm children.BMC oral health · 2026Observational
- Prospective genomic and epidemiologic surveillance of Klebsiella pneumoniae in a tertiary NICU.Antimicrobial resistance and infection control · 2026Article
- Infection prevention and control ofAntimicrobial stewardship & healthcare epidemiology : ASHE · 2026Review
- Human milk microbiota: origins, determinants, and roles in maternal-infant microbial transmission and infant microbiome assembly.Frontiers in microbiology · 2026Review
- Management of Neonates in the Special Care Nursery and Its Impact on the Developing Gut Microbiota: A Comprehensive Clinical Review.Microorganisms · 2025Review
- Effect of Skin-to-Skin Care on the Day of Birth on Skin Colonization in Preterm Infants: A Pre- and Post-Implementation Study.Children (Basel, Switzerland) · 2024Article
- Les soins peau-à-peau chez les nourrissons à terme et prématurés.Paediatrics & child health · 2024Review
- Skin-to-skin care (SSC) for term and preterm infants.Paediatrics & child health · 2024Review
- Evaluation of a complex couplet care intervention in a neonatal intensive care unit: A mixed methods study protocol.Pediatric investigation · 2024Article
- A Scoping Review of the Oral Microbiome in Preterm Infants.American journal of perinatology · 2024Article
- Contact with caregivers is associated with composition of the infant gastrointestinal microbiome in the first 6 months of life.American journal of biological anthropology · 2024Article
- Impact of Kangaroo Mother Care on Skin Microbiome of Very Preterm Infants - A Pilot Study.Indian journal of pediatrics · 2024Article
- A gut instinct for childhood leukemia prevention: microbiome-targeting recommendations aimed at parents and caregivers.Frontiers in public health · 2024Review
- Microbiome dysbiosis: a modifiable state and target to prevent Staphylococcus aureus infections and other diseases in neonates.Journal of perinatology : official journal of the California Perinatal Association · 2024Review
- The Maternal Microbiome and Gestational Diabetes Mellitus: Cause and Effect.Microorganisms · 2023Review
- Early skin-to-skin contact and risk of late-onset-sepsis in very and extremely preterm infants.Pediatric research · 2023Observational
- Effect on neonatal sepsis following immediate kangaroo mother care in a newborn intensive care unit: a post-hoc analysis of a multicentre, open-label, randomised controlled trial.EClinicalMedicine · 2023Article
- Effect of early directed implementation of family-integrated care measures on colonisation withBMJ paediatrics open · 2023Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectiveThe oral cavity represents an initial entry way for oral and gut indigenous colonization. Skin-to-skin (STS) care, in which the mother holds the diaper clad naked preterm (PT) infant between her breasts, is associated with improved digestive function, decreased stress, and improved survival. This study evaluated the development of oral microbial colonization repertoires and health characteristics in PT infants with or without STS exposure.
methodsSaliva from 42 PT infants (<32 weeks of gestation at birth) was collected prospectively at 1 month and/or at discharge. High-throughput 16S rRNA sequencing identified microbial diversity and prevalence of bacterial signatures correlated with clinical STS or non-STS care.
resultsCorrected for gestational age (CGA) at sampling, bacterial taxa demonstrated increased Streptococcus as a signature of oral repertoire maturation. STS was associated with increased Streptococcus (p < 0.024), while non-STS was associated with greater Corynebacterium (p < 0.023) and Pseudomonas (p < 0.019) in infants ≤ 32 weeks CGA. In infants > 32 weeks CGA, Neisseria and Acinetobacter were more prevalent, 50 vs. 16.7% and 40 vs. 0%, respectively. STS care was associated with shorter hospitalization (p < 0.039).
conclusionSTS care during earlier gestation was associated with a distinct microbial pattern and an accelerated pace of oral microbial repertoire maturity.
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