Evidence map›Paper›PMID 26006734›Full record

ReviewFertility and sterility2015

Cost and efficacy comparison of in vitro fertilization and tubal anastomosis for women after tubal ligation.

Lauren B Messinger, Connie E Alford, John M Csokmay, Melinda B Henne, Sunni L Mumford, James H Segars, Alicia Y Armstrong

Open access · bronzeAbstract readComparative StudyReview
In one paragraph

Review in Fertility and sterility, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Observational
  9. Review
  10. Article
  11. Article
  12. Article
  13. Where Microsurgical Tubal Reanastomosis Stands in theGynecology and minimally invasive therapy
    Review
  14. A Novel Technique for Essure Reversal.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Lauren B MessingerDepartment of Obstetrics and Gynecology, St. Vincent Women's Hospital, Indianapolis, Indiana. Electronic address: lmessing@stvincent.org.
Connie E AlfordSouth Florida Institute for Reproductive Medicine, Naples, Florida.
John M CsokmayDivision of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Walter Reed National Military Medical Center, Bethesda, Maryland.
Melinda B HenneReproductive Medicine Associates of Texas, San Antonio, Texas.
Sunni L MumfordEpidemiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
James H SegarsReproductive Science and Women's Health Research, Department of Obstetrics and Gynecology, Johns Hopkins University, Baltimore, Maryland.
Alicia Y ArmstrongProgram in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Eunice Kennedy Shriver National Institute of Child Health and Human Development · USInstitute for Reproductive Health · USJohns Hopkins University · USNational Institutes of Health · USWalter Reed National Military Medical Center · USWomen's Hospital · US

Funding

Reproductive Endocrinology And Infertility Clinical Training ProgramZIEHD008737 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI HILL, MICAH · 2011 to 2025
$24.0M
Intramural NIH HHS Z99 HD999999Intramural NIH HHS ZIE HD008737
6 · The paper itself

Abstract

objectiveTo compare cost and efficacy of tubal anastomosis to in vitro fertilization (IVF) in women who desired fertility after a tubal ligation.

designCost-effectiveness analysis.

settingNot applicable. PATIENT(S): Not applicable. INTERVENTION(S): Not applicable. MAIN OUTCOME MEASURE(S): Cost per ongoing pregnancy. RESULT(S): Cost per ongoing pregnancy for women after tubal anastomosis ranged from $16,446 to $223,482 (2014 USD), whereas IVF ranged from $32,902 to $111,679 (2014 USD). Across maternal age groups <35 and 35-40, years tubal anastomosis was more cost effective than IVF for ongoing pregnancy. Sensitivity analyses validated these findings across a wide range of ongoing pregnancy probabilities as well as costs per procedure. CONCLUSION(S): Tubal anastomosis was the most cost-effective approach for most women less than 41 years of age, whereas IVF was the most cost-effective approach for women aged ≥41 years who desired fertility after tubal ligation. A model was created that can be modified based on cost and success rates in individual clinics for improved patient counseling.

Indexed as

Cost-Benefit AnalysisDecision TreesAdultAnastomosis, SurgicalFallopian TubesFemaleFertilization in VitroHumansPregnancySterilization, Tubalbilateral tubal anastomosis (BTA)cost effectivenessdecision treeIn vitro fertilization (IVF)tubal reversal

Identifiers

PMID26006734
PMCPMC4710374
OpenAlexW2167905032

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.