ArticleJournal of anxiety disorders2015
Anxiety sensitivity and the anticipation of predictable and unpredictable threat: Evidence from the startle response and event-related potentials.
Article in Journal of anxiety disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The trial behind it
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Who cites it
30 citing papers in PubMed, 52 citations in OpenAlex.
- Exploratory Investigation of a Brief Cognitive Behavioral Intervention and Transcranial Direct Current Stimulation on Odor Sensitivity.Psychosomatic medicine · 2019Trial
- Attentional processing in individual anxiety: Electrocortical correlates of threat- and safety-related declarative memory formation.Cognitive, affective & behavioral neuroscience · 2026Article
- Multidimensional Determinants of Sexual Dysfunction in Multiple Sclerosis: Incremental Insights from a Hierarchical Model.Journal of clinical medicine · 2026Article
- Mediating effect of fear of happiness between intolerance of uncertainty and anxiety among Lebanese adults.Global mental health (Cambridge, England) · 2026Article
- Ready for translation: non-invasive auricular vagus nerve stimulation inhibits psychophysiological indices of stimulus-specific fear and facilitates responding to repeated exposure in phobic individuals.Translational psychiatry · 2025Article
- Trait state occasion (TSO) modeling of event-related potentials (ERPs).Biological psychology · 2025Article
- Predictive coding in psychopathology: mechanistic model or metaphorical re-description?Frontiers in human neuroscience · 2025Review
- Evaluating Family Coping Mechanisms in Pediatric Seizure Disorders: From Emergency Room to Long-Term Follow-Up.Pediatric reports · 2024Article
- Neuroimaging-based evidence for sympathetic correlation between brain activity and peripheral vasomotion during pain anticipation.Scientific reports · 2024Article
- Normalizing Uncertain Threat: What Change in Anxiety-Potentiated Startle Can Tell Us About Anxiety Treatment.Biological psychiatry · 2024Article
- Don't worry, it won't be fine. Contributions of worry and anxious arousal to startle responses and event-related potentials in threat anticipation.Cognitive, affective & behavioral neuroscience · 2023Article
- Situational uncertainty interacts with anxiety sensitivity and distress intolerance to predict anticipated worry and preparation for a hurricane.Anxiety, stress, and coping · 2023Article
- Effects of early childhood behavioral inhibition and parental anxiety disorder on adolescents' startle response to predictable and unpredictable threat.Research on child and adolescent psychopathology · 2022Article
- Integrating NIMH's Research Domain Criteria (RDoC) Initiative into Psychiatry Resident Training.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2022Article
- Differential effects of the translocator protein 18 kDa (TSPO) ligand etifoxine and the benzodiazepine alprazolam on startle response to predictable threat in a NPU-threat task after acute and short-term treatment.Psychopharmacology · 2022Article
- Event-related potentials to acoustic startle probes during unpredictable threat are associated with individual differences in intolerance of uncertainty.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2022Article
- Posttraumatic stress symptom dimensions and brain responses to startling auditory stimuli in combat veterans.Journal of abnormal psychology · 2021Article
- Shared and unique neural circuitry underlying temporally unpredictable threat and reward processing.Social cognitive and affective neuroscience · 2021Article
- Gender differences in anxiety: The mediating role of sensitivity to unpredictable threat.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2020Article
- Preparing for the Worst: Evidence that Older Adults Proactively Downregulate Negative Affect.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
There is growing evidence that heightened sensitivity to unpredictable threat is a core mechanism of dysfunction in anxiety disorders. However, it is unclear whether anxiety sensitivity is also associated with sensitivity to unpredictable threat. In the present study, 131 participants completed the Anxiety Sensitivity Index-3, which includes physical concerns (PC), social concerns (SC), and cognitive concerns (CC) subscales, and a predictable vs. unpredictable threat-of-shock task. Startle eyeblink and ERP responses (N100, P300) to the acoustic startle probes were measured during the task. PC and CC were associated with heightened and attenuated, respectively, startle for the unpredictable (but not predictable) condition. CC were also associated with attenuated probe N100 for the unpredictable condition only, and PC were associated with increased P300 suppression across the predictable and unpredictable conditions. This study provides novel evidence that the different anxiety sensitivity dimensions demonstrate unique relationships with the RDoC domains "acute" and "potential" threat.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.