Evidence map›Paper›PMID 26005713›Full record

ArticleInternational journal of anesthetics and anesthesiology

Long-Term Function, Pain and Medication Use Outcomes of Radiofrequency Ablation for Lumbar Facet Syndrome.

Zachary L McCormick, Benjamin Marshall, Jeremy Walker, Robert McCarthy, David R Walega

2 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in International journal of anesthetics and anesthesiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03444493 nacompletednot on this map

The Effect of Stabilization Exercises on Pain, Disability and Physical Performance After Radiofrequency Lumbar Facet Denervation

TypeinterventionalSponsorHacettepe UniversityRan2015 to 2016Enrolled39ConditionsLow Back Pain, Facet Joint Pain, Radiofrequency Denervation, PainArmsExercise
NCT06666621 phase4recruitingnot on this map

Antagonism of Endogenous Opioids: Use in Interpretation of Injections

TypeinterventionalSponsorMiddle Tennessee Research InstituteRan2024 to 2026Enrolled33ConditionsLow Back Pain, Zygapophyseal Joint ArthritisArmsNormal saline infusion, Naloxone infusion
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 72 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zachary L McCormickThe Rehabilitation Institute of Chicago/Northwestern University Feinberg School of Medicine, Department of Physical Medicine and Rehabilitation, USA.
Benjamin MarshallThe Rehabilitation Institute of Chicago/Northwestern University Feinberg School of Medicine, Department of Physical Medicine and Rehabilitation, USA.
Jeremy WalkerNorthwestern University Feinberg School of Medicine, Department of Anesthesiology, USA.
Robert McCarthyNorthwestern University Feinberg School of Medicine, Department of Anesthesiology, USA.
David R WalegaNorthwestern University Feinberg School of Medicine, Department of Anesthesiology, USA.
Northwestern University · US

Funding

Short Term Research Training for Medical StudentsT35DK060441 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI WOLF, BRYAN A · 2002 to 2011
$543k
NIDDK NIH HHS T35 DK060441
6 · The paper itself

Abstract

objectiveRadiofrequency ablation (RFA) of the medial branch nerves for facet-mediated low back pain demonstrates clinical benefit for 6-12 months and possibly up to 2 years. This study investigated function, pain, and medication use outcomes of RFA for lumbar facet syndrome in a cohort with long-term follow-up.

methodsIndividuals evaluated in a tertiary academic pain practice between January, 2007-December, 2013, 18-60 years of age, with a clinical and radiologic diagnosis of lumbar facet syndrome, who underwent ≥1set of diagnostic medial branch blocks with resultant >75% pain relief and subsequent RFA were included. Outcomes measured were the proportion of individuals who reported ≥50% improvement in function, ≥50% improvement in pain; change in median NRS pain score, daily morphine equivalent consumption (DME), Medication Quantification Scale III (MSQ III) score and procedure complications.

resultsSixty-two consecutive individuals with a median age and 25%-75% interquartile range (IQR) of 34 years (35, 52) met inclusion criteria. Seven individuals were lost to follow-up. Duration of pain was <2 years in 42%, 2-5 years in 40%, >5 years in 18% of individuals. Median duration of follow-up was 39 months (16, 60). Function and pain improved by ≥50% in 58% (CI 45%, 71%) and 53% (CI 40%, 66%) of individuals, respectively. The median reduction in MQS III score was 3.4 points (0, 8.8). No complications occurred in this cohort.

conclusionsThis study demonstrates a durable treatment effect of RFA for lumbar facet syndrome at long-term follow-up, as measured by improvement in function, pain, and analgesic use.

Indexed as

DenervationLow back painOpioid analgesicsZygapophyseal joint

Identifiers

PMID26005713
PMCPMC4440581
OpenAlexW2187480840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.