Evidence map›Paper›PMID 26005686›Full record

ArticleJournal of neuroinfectious diseases2015

MicroRNAs and Malaria - A Dynamic Interaction Still Incompletely Understood.

Amy Cohen, Valéry Combes, Georges Er Grau

Open access · hybridAbstract read
In one paragraph

Article in Journal of neuroinfectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. "Dual-gene" malaria-resistance: Therapeutically-rational exchange (T-REX) of group-O sickle trait and group-O C-traittrait red blood cells can be evaluated in Benin and Nigeria.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2020
    Article
  4. Pathology's historic 2019 incoming residents: Why "the internationalization of pathology" may markedly advance transfusion medicine and cellular therapeutics.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Amy CohenVascular Immunology Unit, Discipline of Pathology, School of Medical Sciences & Marie Bashir Institute, The University of Sydney, Australia.
Valéry CombesVascular Immunology Unit, Discipline of Pathology, School of Medical Sciences & Marie Bashir Institute, The University of Sydney, Australia.
Georges Er GrauVascular Immunology Unit, Discipline of Pathology, School of Medical Sciences & Marie Bashir Institute, The University of Sydney, Australia.
The University of Sydney · AU

Funding

Microparticles, a new player in cerebral malaria pathogenesisR01NS079873 · NINDS · LA JOLLA INFECTIOUS DISEASE INSTITUTE · PI COMBES, VALERY MADELEINE · 2012 to 2015
$1.3M
NINDS NIH HHS R01 NS079873
6 · The paper itself

Abstract

Malaria is a mosquito-borne infectious disease caused by parasitic protozoa of the genus Plasmodium. It remains a major problem affecting humans today, especially children. However, the pathogenesis of malaria, especially severe malaria, remains incompletely understood, hindering our ability to treat this disease. Of recent interest is the role that small, non-coding RNAs play in the progression, pathogenesis of, and resistance to, malaria. Independent studies have now revealed the presence of microRNA (miRNA) in the malaria parasite, vector, and host, though these studies are relatively few. Here, we review these studies, focusing on the roles specific miRNA have in the disease, and how they may be harnessed for therapeutic purposes.

Indexed as

ImmunopathologyInflammationMalariamicroRNAProtective immunity

Identifiers

PMID26005686
PMCPMC4441219
OpenAlexW2127145122

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.