ArticleFrontiers in microbiology2015
Impact of metabolism and growth phase on the hydrogen isotopic composition of microbial fatty acids.
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 50 citations in OpenAlex.
- Alkane-oxidizing consortia produce substantial amounts of disaccharides.Frontiers in microbiology · 2026Article
- Large enrichments in fatty acidProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Central Metabolism and Growth Rate Impacts on Hydrogen and Carbon Isotope Fractionation During Amino Acid Synthesis inFrontiers in microbiology · 2022Article
- Article
- Chemoorganotrophic Bacteria From Lake Fryxell, Antarctica, IncludingFrontiers in microbiology · 2019Article
- Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression.World journal of gastroenterology · 2017Article
- Minimal Influence of [NiFe] Hydrogenase on Hydrogen Isotope Fractionation in HFrontiers in microbiology · 2017Article
- Transhydrogenase and Growth Substrate Influence Lipid Hydrogen Isotope Ratios in Desulfovibrio alaskensis G20.Frontiers in microbiology · 2016Article
- Fractionation of Hydrogen Isotopes by Sulfate- and Nitrate-Reducing Bacteria.Frontiers in microbiology · 2016Article
- Mixoplankton and mixotrophy: future research priorities.Journal of plankton researchReview
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Authors and funding
6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Microorganisms are involved in all elemental cycles and therefore it is important to study their metabolism in the natural environment. A recent technique to investigate this is the hydrogen isotopic composition of microbial fatty acids, i.e., heterotrophic microorganisms produce fatty acids enriched in deuterium (D) while photoautotrophic and chemoautotrophic microorganisms produce fatty acids depleted in D compared to the water in the culture medium (growth water). However, the impact of factors other than metabolism have not been investigated. Here, we evaluate the impact of growth phase compared to metabolism on the hydrogen isotopic composition of fatty acids of different environmentally relevant microorganisms with heterotrophic, photoautotrophic and chemoautotrophic metabolisms. Fatty acids produced by heterotrophs are enriched in D compared to growth water with εlipid/water between 82 and 359‰ when grown on glucose or acetate, respectively. Photoautotrophs (εlipid/water between -149 and -264‰) and chemoautotrophs (εlipid/water between -217 and -275‰) produce fatty acids depleted in D. Fatty acids become, in general, enriched by between 4 and 46‰ with growth phase which is minor compared to the influence of metabolisms. Therefore, the D/H ratio of fatty acids is a promising tool to investigate community metabolisms in nature.
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