Evidence map›Paper›PMID 26005322›Full record

ArticleCancer informatics2015

BioMiner: Paving the Way for Personalized Medicine.

Chris Bauer, Karol Stec, Alexander Glintschert, Kristina Gruden, Christian Schichor, Michal Or-Guil, Joachim Selbig, Johannes Schuchhardt

Abstract read
In one paragraph

Article in Cancer informatics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Visual analysis of multi-omics data.Frontiers in bioinformatics · 2024
    Article
  3. Article
  4. Article
  5. BcCluster: A Bladder Cancer Database at the Molecular Level.Bladder cancer (Amsterdam, Netherlands) · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chris BauerResearch and Development, MicroDiscovery GmbH, Berlin, Germany.
Karol StecResearch and Development, MicroDiscovery GmbH, Berlin, Germany.
Alexander GlintschertResearch and Development, MicroDiscovery GmbH, Berlin, Germany.
Kristina GrudenDepartment for Biotechnology and Systems Biology, National Institute of Biology, Ljubljana, Slovenia.
Christian SchichorDepartment of Neurosurgery, Klinikum der Ludwig-Maximilian-Universität München, Munich, Germany.
Michal Or-GuilSystems Immunology Lab, Department of Biology, Humboldt University, Berlin, Germany. ; Research Center ImmunoSciences, Charité University of Medicine Berlin, Berlin, Germany.
Joachim SelbigInstitute of Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Johannes SchuchhardtResearch and Development, MicroDiscovery GmbH, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Personalized medicine is promising a revolution for medicine and human biology in the 21st century. The scientific foundation for this revolution is accomplished by analyzing biological high-throughput data sets from genomics, transcriptomics, proteomics, and metabolomics. Currently, access to these data has been limited to either rather simple Web-based tools, which do not grant much insight or analysis by trained specialists, without firsthand involvement of the physician. Here, we present the novel Web-based tool "BioMiner," which was developed within the scope of an international and interdisciplinary project (SYSTHER) and gives access to a variety of high-throughput data sets. It provides the user with convenient tools to analyze complex cross-omics data sets and grants enhanced visualization abilities. BioMiner incorporates transcriptomic and cross-omics high-throughput data sets, with a focus on cancer. A public instance of BioMiner along with the database is available at http://systherDB.microdiscovery.de/, login and password: "systher"; a tutorial detailing the usage of BioMiner can be found in the Supplementary File.

Indexed as

biomarker detectioncancerdata miningmultiomics data integrationpathway visualizationpersonalized medicine

Identifiers

PMID26005322
PMCPMC4406277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.