ReviewClinics in laboratory medicine2015
Multiplex polymerase chain reaction tests for detection of pathogens associated with gastroenteritis.
Review in Clinics in laboratory medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Healthcare-Associated Gastroenteritis: Outbreak Report and Systematic Review of the Literature.Journal of the Pediatric Infectious Diseases Society · 2025Pooled it
- Global distribution of sporadic sapovirus infections: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA).Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Guideline
- Evaluation of the Hologic Panther Fusion investigational use only assays for gastrointestinal bacterial pathogens.Journal of clinical microbiology · 2025Article
- Kogene PowerChek Multiplex Real-time PCR Kits Versus the BioFire FilmArray Gastrointestinal Panel: Roles of Crossing Point Values and Melting Curves in Interpreting the FilmArray Gastrointestinal Panel.Annals of laboratory medicine · 2025Article
- Multicenter evaluation of the QIAstat-Dx Gastrointestinal Panel 2, a multiplex PCR platform for the diagnosis of acute gastroenteritis.Journal of clinical microbiology · 2025Article
- Feline enteropathogens and molecular diagnostics: benefits, limitations and clinical applications.Journal of feline medicine and surgery · 2025Review
- Performance evaluation of the Biosynex AMPLIQUICK Fecal Bacteriology PCR kit.BMC microbiology · 2025Article
- A Game Changer for Acute Gastroenteritis in the Pediatric Emergency Department: Multiplex Stool PCR Test.Journal of clinical laboratory analysis · 2025Article
- Adaptation and validation of a gastrointestinal panel to detect diarrheal virus pathogens on a high-throughput qPCR system.Medical microbiology and immunology · 2025Article
- A novel comparative evaluation of multiplex PCR panels for gastrointestinal pathogen detection: Seegene Allplex™ vs. Luminex NxTAGEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Article
- Use of gastrointestinal syndromic multiplex molecular assays and detection ofJournal of clinical microbiology · 2025Article
- Article
- Clinical detection of four emerging canine diarrhea-associated viruses and evolutionary analysis of canine kobuvirus.Archives of virology · 2024Article
- Clinical Performance of the LiquidArrayDiagnostics (Basel, Switzerland) · 2024Article
- Evaluation of the Allplex GI Parasite and Helminth PCR Assay in a Belgian Travel Clinic.Diagnostics (Basel, Switzerland) · 2024Article
- Microbial Contamination of Food: Probiotics and Postbiotics as Potential Biopreservatives.Foods (Basel, Switzerland) · 2024Review
- Gastrointestinal Panel Performance for the Diagnosis of Acute Gastroenteritis in Pediatric Patients.Cureus · 2024Article
- Article
- Enhancing enteric pathogen detection: implementation and impact of multiplex PCR for improved diagnosis and surveillance.BMC infectious diseases · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
A wide range of enteric pathogens can cause infectious gastroenteritis. Conventional diagnostic algorithms are time-consuming and often lack sensitivity and specificity. Advances in molecular technology have provided new clinical diagnostic tools. Multiplex polymerase chain reaction (PCR)-based testing has been used in gastroenterology diagnostics in recent years. This article presents a review of recent laboratory-developed multiplex PCR tests and current commercial multiplex gastrointestinal pathogen tests. It focuses on two commercial syndromic multiplex tests: Luminex xTAG Gastrointestinal Pathogen Panel and BioFire FilmArray gastrointestinal test. Multiplex PCR tests have shown superior sensitivity to conventional methods for detection of most pathogens.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.