ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2015
Photopic full-field electroretinography and optical coherence tomography in type 1 diabetic retinopathy.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 37 citations in OpenAlex.
- Screening for diabetic retinopathy using new mydriasis-free, full-field flicker ERG recording device.Scientific reports · 2016Trial
- Loss of ATRAID in Late-Onset, Non-Syndromic Retinitis Pigmentosa.Investigative ophthalmology & visual science · 2026Article
- The Mydriasis-Free Handheld ERG Device and Its Utility in Clinical Practice: A Review.Biomedicines · 2026Review
- Sustained Benefit of Short-Term Levodopa Treatment on Inner Retinal Function in Patients With Diabetes.Translational vision science & technology · 2025Article
- Efficacy and safety of Nd: YAG laser vitreolysis in patients with physiological vitreous floaters.BMC ophthalmology · 2025Article
- The negative off-response driven by M-cone and depolarizing bipolar cell in the rat electroretinogram.Scientific reports · 2025Article
- Comparisons of oscillatory potentials and 30 Hz flicker electroretinograms for discriminating eyes with diabetic retinopathy from normal eyes.Japanese journal of ophthalmology · 2025Observational
- Electrophysiological findings in long-term type 1 diabetes patients without diabetic retinopathy using different ERG recording systems.Scientific reports · 2024Article
- Multifocal electroretinogram changes after panretinal photocoagulation in early proliferative diabetic retinopathy.Medical hypothesis, discovery & innovation ophthalmology journal · 2024Article
- Retinal Functional Impairment in Diabetic Retinopathy.Biomedicines · 2023Article
- Full-field electroretinogram recorded with skin electrodes in 6- to 12-year-old children.Documenta ophthalmologica. Advances in ophthalmology · 2023Article
- Full-field and multifocal electroretinogram in non-diabetic controls and diabetics with and without retinopathy.Acta ophthalmologica · 2022Article
- MD2 blockade prevents modified LDL-induced retinal injury in diabetes by suppressing NADPH oxidase-4 interaction with Toll-like receptor-4.Experimental & molecular medicine · 2021Article
- Reproducibility of Fixed-luminance and Multi-luminance Flicker Electroretinography in Patients With Diabetic Retinopathy Using an Office-based Testing Paradigm.Journal of diabetes science and technology · 2020Observational
- Retinal vasculature-function correlation in non-proliferative diabetic retinopathy.Documenta ophthalmologica. Advances in ophthalmology · 2020Article
- Targeting long non-coding RNA MALAT1 alleviates retinal neurodegeneration in diabetic mice.International journal of ophthalmology · 2020Article
- AMPLITUDE LOSS OF THE HIGH-FREQUENCY FLICKER ELECTRORETINOGRAM IN EARLY DIABETIC RETINOPATHY.Retina (Philadelphia, Pa.) · 2019Article
- Temporal Frequency Abnormalities in Early-Stage Diabetic Retinopathy Assessed by Electroretinography.Investigative ophthalmology & visual science · 2018Article
- The Relationship between Peripheral Nerve Conduction Velocity and Ophthalmological Findings in Type 2 Diabetes Patients with Early Diabetic Retinopathy.Journal of ophthalmology · 2018Article
- Clinical biomarkers and molecular basis for optimized treatment of diabetic retinopathy: current status and future prospects.Eye and brain · 2016Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to evaluate the role of photopic full-field electroretinography (ERG) and retinal thickness measurements by spectral-domain optical coherence tomography (SD-OCT) in the assessment of disease severity in type 1 diabetic retinopathy.
methodsA population-based cohort of 151 patients with type 1 diabetes underwent a complete ophthalmic examination, including photopic full-field ERG and SD-OCT for retinal thickness measurements. Stereoscopic fundus photographs were taken according to the Early Treatment Diabetic Retinopathy Study protocol, and the classification of diabetic retinopathy was based on the International Clinical Diabetic Retinopathy Disease Severity Scale. Associations between photographically determined retinopathy level, b-wave amplitude and peak time of the photopic single-flash and 30-Hz flicker ERG, and central retinal thickness parameters were evaluated.
resultsFor all ERG measurements, the amplitude decreased and peak time increased with progression of the disease, but these associations lost statistical significance after adjusting for age and excluding laser-treated patients. Mean retinal thickness was significantly associated with the b-wave amplitude of photopic single-flash and 30-Hz flicker responses (r(2) = 0.08, p = 0.006; and r(2) = 0.05, p = 0.025, respectively), but revealed no association with retinopathy level.
conclusionsPhotopic full-field ERG and SD-OCT-derived retinal thickness parameters have limited clinical value in the staging of diabetic retinopathy. However, thinning of the central retina leads to significant functional impairment and may reflect an ongoing neurodegenerative process in the retinal tissue.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.