Evidence map›Paper›PMID 26003997›Full record

ArticleThe Journal of pediatrics2015

Sympathetic Activity Assessed during Exercise Recovery in Young Obese Females.

R Lee Franco, Stacey H Privett, Mary K Bowen, Edmund O Acevedo, James A Arrowood, Edmond P Wickham, Ronald K Evans

Registry-linked trialAbstract read
In one paragraph

Article in The Journal of pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00562293, which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00562293 no registry record found
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

R Lee FrancoDepartment of Kinesiology and Health Sciences, College of Humanities and Sciences, Virginia Commonwealth University, Richmond, VA. Electronic address: francorl@vcu.edu.
Stacey H PrivettDepartment of Kinesiology and Health Sciences, College of Humanities and Sciences, Virginia Commonwealth University, Richmond, VA.
Mary K BowenDepartment of Kinesiology and Health Sciences, College of Humanities and Sciences, Virginia Commonwealth University, Richmond, VA.
Edmund O AcevedoDepartment of Kinesiology and Health Sciences, College of Humanities and Sciences, Virginia Commonwealth University, Richmond, VA.
James A ArrowoodDivision of Cardiology, Department of Internal Medicine, School of Medicine, Virginia Commonwealth University, Richmond, VA.
Edmond P WickhamDivision of Endocrinology and Metabolism, Departments of Internal Medicine and Pediatrics, School of Medicine, Virginia Commonwealth University, Richmond, VA.
Ronald K EvansDepartment of Kinesiology and Health Sciences, College of Humanities and Sciences, Virginia Commonwealth University, Richmond, VA.
Virginia Commonwealth University · US

Funding

Center for Clinical and Translational ResearchUL1TR000058 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2012 to 2015
$12.5M
Adiponectin and Endothelial Dysfunction in AdolescentsK23HD053742 · NICHD · VIRGINIA COMMONWEALTH UNIVERSITY · PI WICKHAM, EDMOND PRYCE · 2009 to 2013
$673k
NCATS NIH HHS UL1 TR000058NICHD NIH HHS K23 HD053742NICHD NIH HHS K23-HD053742
6 · The paper itself

Abstract

objectiveTo evaluate differences in sympathetic activity, as assessed by an exercise recovery index (ERI; heart rate/oxygen consumption [VO2] plateau), between black and white obese female adolescents. An additional aim was to determine the association of ERI with insulin resistance (homeostasis model assessment of insulin resistance [HOMA-IR]), cardiovascular fitness per fat-free mass (VO2 per fat-free mass), systolic blood pressure (SBP), and percent body fat (%FAT) in both black and white obese adolescents. STUDY

designSixty-one females volunteered to participate in this study. HOMA-IR, SBP, and %FAT were assessed during resting conditions in black (n = 49, 13.7 ± 1.6 years, 38.1 ± 6.1 kg/m(2)) and white (n = 12, 13.3 ± 2.2 years, 34.3 ± 4.9 kg/m(2)) obese adolescents. An ERI was calculated during a 5-minute passive recovery period immediately following a graded treadmill exercise test to exhaustion.

resultsThe ERI was significantly greater in black compared with white obese adolescent females (29.8 ± 6.4 vs 24.1 ± 3.1 bpm·mLO2(-1)·min(-1), P = .004). Using multiple linear regression modeling, there was a significant independent association between ERI and VO2 per fat-free mass (r = -0.310, P = .027) and %FAT (r = 0.326, P = .020) in black obese adolescents after controlling for HOMA-IR and SBP.

conclusionsThese results suggest that black obese adolescent females have greater sympathetic activity, as assessed by an ERI, than white obese adolescent females. These findings support the need for weight management efforts aimed at both reducing %FAT and improving fitness in obese adolescents, specifically black females.

trial registrationRegistered with Clinicaltrials.gov: NCT00562293.

Indexed as

Black or African AmericanWhite PeopleAdolescentAge FactorsChildExerciseExercise ToleranceFemaleHeart RateHumansObesityOxygen ConsumptionRisk FactorsSex FactorsSympathetic Nervous System

Identifiers

PMID26003997
PMCPMC4516681
OpenAlexW1530291766

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.