Evidence map›Paper›PMID 26003436›Full record

Trial reportContemporary clinical trials2015

The Telehealth Enhancement of Adherence to Medication (TEAM) in pediatric IBD trial: Design and methodology.

Kevin A Hommel, Wendy N Gray, Elizabeth Hente, Katherine Loreaux, Richard F Ittenbach, Michele Maddux, Robert Baldassano, Francisco Sylvester, Wallace Crandall, Charles Doarn and 3 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Psychological interventions for treatment of inflammatory bowel disease.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Remote care through telehealth for people with inflammatory bowel disease.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Risk Factors for Loss to Follow Up in Pediatric Supracondylar Humerus Fractures.Journal of the Pediatric Orthopaedic Society of North America · 2024
    Article
  7. Review
  8. Article
  9. Hybrid Concept Analysis of Self-Management Support: School Nurses Supporting Students with Psychogenic Nonepileptic Seizures.The Journal of school nursing : the official publication of the National Association of School Nurses · 2022
    Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kevin A HommelCincinnati Children's Hospital Medical Center, United States; University of Cincinnati College of Medicine, United States. Electronic address: kevin.hommel@cchmc.org.
Wendy N GrayAuburn University, United States.
Elizabeth HenteCincinnati Children's Hospital Medical Center, United States.
Katherine LoreauxCincinnati Children's Hospital Medical Center, United States.
Richard F IttenbachCincinnati Children's Hospital Medical Center, United States; University of Cincinnati College of Medicine, United States.
Michele MadduxChildren's Mercy Hospitals and Clinics, United States; University of Missouri Kansas City School of Medicine, United States.
Robert BaldassanoChildren's Hospital of Philadelphia, United States; University of Pennsylvania School of Medicine, United States.
Francisco SylvesterUniversity of North Carolina, United States.
Wallace CrandallNationwide Children's Hospital, United States; Ohio State University College of Medicine, United States.
Charles DoarnUniversity of Cincinnati, United States.
Melvin B HeymanUCSF Benioff Children's Hospital, United States; University of California, San Francisco, United States.
David KeljoChildren's Hospital of Pittsburgh, United States; University of Pittsburgh School of Medicine, United States.
Lee A DensonCincinnati Children's Hospital Medical Center, United States; University of Cincinnati College of Medicine, United States.

Funding

Stem Cell/Organoid and Genome Editing CoreP30DK078392 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Alexander Miethke · 2007 to 2026
$24.4M
Telehealth Enhancement of Adherence to Medication in Pediatric IBD (TEAM Study)R01HD067174 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI HOMMEL, KEVIN · 2011 to 2015
$2.7M
NICHD NIH HHS R01 HD067174NIDDK NIH HHS P30 DK078392
6 · The paper itself

Abstract

Medication nonadherence is a significant health care issue requiring regular behavioral treatment. Lack of sufficient health care resources and patient/family time commitment for weekly treatment are primary barriers to receiving appropriate self-management support. We describe the methodology of the Telehealth Enhancement of Adherence to Medication (TEAM) trial for medication nonadherence in pediatric inflammatory bowel disease (IBD). For this trial, participants 11-18 years of age will be recruited from seven pediatric hospitals and will complete an initial 4-week run in to assess adherence to a daily medication. Those who take less than 90% of their prescribed medication will be randomized. A total of 194 patients with IBD will be randomized to either a telehealth behavioral treatment (TBT) arm or education only (EO) arm. All treatments will be delivered via telehealth video conferencing. The patients will be assessed at baseline, post-treatment, 3, 6, and 12 months. We anticipate that participants in the TBT arm will demonstrate a statistically significant improvement at post-treatment and 3-, 6-, and 12-month follow-up compared to participants in the EO arm for both medication adherence and secondary outcomes (i.e., disease severity, patient quality of life, and health care utilization). If efficacious, the TEAM intervention could be disseminated broadly and reduce health care access barriers so that the patients could receive much needed self-management intervention.

Indexed as

Medication AdherenceResearch DesignSelf CareAdolescentChildFemaleHealth ServicesHumansInflammatory Bowel DiseasesInternetMalePatient Education as TopicQuality of LifeReminder SystemsSeverity of Illness IndexTelemedicineAdherenceBehavioralInflammatory bowel diseasePediatricsTelehealth

Identifiers

PMID26003436
PMCPMC4522393

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.