ReviewTrends in genetics : TIG2015
It's more than stamp collecting: how genome sequencing can unify biological research.
Review in Trends in genetics : TIG, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- The Genomics Revolution in Nonmodel Species: Predictions vs. Reality for Salmonids.Molecular ecology · 2025Review
- The Ecological Genome Project and the Promises of Ecogenomics for Society: Realising a Shared Vision as One Health.Bioethics · 2025Article
- Chromosome-level genome assembly of the dung beetle Catharsius molossus (Coleoptera: Scarabaeidae).Scientific data · 2025Article
- Single-cell and spatial omics unravel the spatiotemporal biology of tumour border invasion and haematogenous metastasis.Clinical and translational medicine · 2024Review
- Article
- MitoHiFi: a python pipeline for mitochondrial genome assembly from PacBio high fidelity reads.BMC bioinformatics · 2023Article
- An Outsider's Perspective on Why We Climb Mountains and Why Projects Like the i5k Matter.Journal of insect science (Online) · 2022Article
- Assessing species coverage and assembly quality of rapidly accumulating sequenced genomes.GigaScience · 2022Article
- Why sequence all eukaryotes?Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Carotenoid modifying enzymes in metazoans.Methods in enzymology · 2022Article
- sppIDer: A Species Identification Tool to Investigate Hybrid Genomes with High-Throughput Sequencing.Molecular biology and evolution · 2018Article
- Earth BioGenome Project: Sequencing life for the future of life.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- A new strategy to infer circularity applied to four new complete frog mitogenomes.Ecology and evolution · 2018Article
- Cytochrome P450 diversity in the tree of life.Biochimica et biophysica acta. Proteins and proteomics · 2018Article
- A strategy for the identification of patterns in the biosynthesis of nonribosomal peptides by Betaproteobacteria species.Scientific reports · 2017Article
- A golden goat genome.Nature genetics · 2017Article
- A Metagenomic Approach to Cyanobacterial Genomics.Frontiers in microbiology · 2017Review
- Molecular classification based on apomorphic amino acids (Arthropoda, Hexapoda): Integrative taxonomy in the era of phylogenomics.Scientific reports · 2016Article
- The Genome and Methylome of a Beetle with Complex Social Behavior, Nicrophorus vespilloides (Coleoptera: Silphidae).Genome biology and evolution · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
The availability of reference genome sequences, especially the human reference, has revolutionized the study of biology. However, while the genomes of some species have been fully sequenced, a wide range of biological problems still cannot be effectively studied for lack of genome sequence information. Here, I identify neglected areas of biology and describe how both targeted species sequencing and more broad taxonomic surveys of the tree of life can address important biological questions. I enumerate the significant benefits that would accrue from sequencing a broader range of taxa, as well as discuss the technical advances in sequencing and assembly methods that would allow for wide-ranging application of whole-genome analysis. Finally, I suggest that in addition to 'big science' survey initiatives to sequence the tree of life, a modified infrastructure-funding paradigm would better support reference genome sequence generation for research communities most in need.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.