Evidence map›Paper›PMID 26003200›Full record

ArticleAmerican journal of surgery2015

A cost analysis of a pancreatic cancer screening protocol in high-risk populations.

Elizabeth Bruenderman, Robert C G Martin

Abstract read
In one paragraph

Article in American journal of surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Economic evaluations of early detection strategies for pancreatic cancer: a systematic review.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Pooled it
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  15. Pancreatic Cancer and Diabetes Mellitus.Current treatment options in gastroenterology · 2018
    Review
  16. Article
  17. Design and Success of a 21st Century Cancer Education Program at the University of Louisville.Journal of cancer education : the official journal of the American Association for Cancer Education · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Elizabeth BruendermanDepartment of Surgery, University of Louisville, Louisville, KY, USA.
Robert C G MartinDepartment of Surgery, University of Louisville, Louisville, KY, USA. Electronic address: Robert.Martin@louisville.edu.

Funding

University of Louisville Cancer Education ProgramR25CA134283 · NCI · UNIVERSITY OF LOUISVILLE · PI HEIN, DAVID W, KIDD, LA CREIS RENEE · 2011 to 2022
$3.1M
NCI NIH HHS R25 CA134283NCI NIH HHS R25-CA-134283
6 · The paper itself

Abstract

backgroundPancreatic cancer is the 4th leading cause of cancer death in the United States. A screening protocol is needed to catch early-stage, resectable disease. This study suggests a protocol for high-risk individuals and assesses the cost in the context of the Affordable Care Act.

methodsMedicare and national average pricing were used for cost analysis of a protocol using magnetic resonance imaging/MRCP biannually in high-risk groups.

resultsCosts per year of life added" based on Medicare and national average costs, respectively, are as follows: $638.62 and $2,542.37 for Peutz-Jeghers syndrome, $945.33 and $3,763.44 for hereditary pancreatitis, $1,141.77 and $4,545.45 for familial pancreatic cancer and "p16-Leiden" mutations, and $356.42 and $1,418.92 for new-onset diabetes over age 50 with weight loss or smoking.

conclusionsA screening program using magnetic resonance imaging/MRCP is affordable in high-risk populations. The United States Preventive Services Task Force must re-evaluate its pancreatic cancer screening guidelines to make screening more cost-effective for the individual.

Indexed as

Cholangiopancreatography, Magnetic ResonanceCosts and Cost AnalysisEndoscopy, Digestive SystemGenetic Predisposition to DiseaseHumansMagnetic Resonance ImagingMass ScreeningPancreatic NeoplasmsPractice Guidelines as TopicRisk FactorsUltrasonographyUnited StatesCost analysisGenetic predispositionHigh riskIdiopathicPancreatic cancerScreening

Identifiers

PMID26003200
PMCPMC4890641

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.