Evidence map›Paper›PMID 26003152›Full record

ArticleEuropean heart journal. Cardiovascular Imaging2016

Multi-phase rotational angiography of the left ventricle to assist ablations: feasibility and accuracy of novel imaging.

Jean-Yves Wielandts, Stijn De Buck, Koen Michielsen, Ruan Louw, Christophe Garweg, Johan Nuyts, Joris Ector, Frederik Maes, Hein Heidbuchel

Abstract read
In one paragraph

Article in European heart journal. Cardiovascular Imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jean-Yves WielandtsDepartment of Cardiovascular Sciences, KU Leuven, Leuven, Belgium Medical Imaging Research Centre, KU Leuven and UZ Leuven, Herestraat 49, Leuven, Belgium jean-yves.wielandts@uzleuven.be.
Stijn De BuckMedical Imaging Research Centre, KU Leuven and UZ Leuven, Herestraat 49, Leuven, Belgium Department of Electrical Engineering, ESAT/PSI, Medical Image Computing, KU Leuven, Leuven, Belgium.
Koen MichielsenMedical Imaging Research Centre, KU Leuven and UZ Leuven, Herestraat 49, Leuven, Belgium Department of Nuclear Medicine and Molecular Imaging, KU Leuven, Leuven, Belgium.
Ruan LouwDepartment of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.
Christophe GarwegDepartment of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.
Johan NuytsMedical Imaging Research Centre, KU Leuven and UZ Leuven, Herestraat 49, Leuven, Belgium Department of Nuclear Medicine and Molecular Imaging, KU Leuven, Leuven, Belgium.
Joris EctorDepartment of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.
Frederik MaesMedical Imaging Research Centre, KU Leuven and UZ Leuven, Herestraat 49, Leuven, Belgium Department of Electrical Engineering, ESAT/PSI, Medical Image Computing, KU Leuven, Leuven, Belgium iMinds-Future Health Department, KU Leuven, Leuven, Belgium.
Hein HeidbuchelHasselt University and Heart Center Hasselt, Diepenbeek, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsInterventional left ventricular (LV) procedures integrating static 3D anatomy visualization are subject to mismatch with dynamic catheter movements due to prominent LV motion. We aimed to evaluate the accuracy of a recently developed acquisition and post-processing protocol for low radiation dose LV multi-phase rotational angiography (4DRA) in patients. METHODS AND

results4DRA image acquisition of the LV was performed as investigational acquisition in patients undergoing left-sided ablation (11 men; BMI = 24.7 ± 2.5 kg/m²). Iodine contrast was injected in the LA, while pacing from the RA at a cycle length of 700 ms. 4DRA acquisition and reconstruction were possible in all 11 studies. Reconstructed images were post-processed using streak artefact reduction algorithms and an interphase registration-based filtering method, increasing contrast-to-noise ratio by a factor 8.2 ± 2.1. This enabled semi-automatic segmentation, yielding LV models of five equidistant phases per cardiac cycle. For evaluation, off-line 4DRA fluoroscopy registration was performed, and the 4DRA LV contours of the different phases were compared with the contours of five corresponding phases of biplane LV angiography, acquired in identical circumstances. Of the distances between these contours, 95% were <4 mm in both incidences. Effective radiation dose for 4DRA, calculated by patient-specific Monte-Carlo simulation, was 5.1 ± 1.1 mSv.

conclusionCreation of 4DRA LV models in man is feasible at near-physiological heart rate and with clinically acceptable radiation dose. They showed high accuracy with respect to LV angiography in RAO and LAO. The presented technology not only opens perspectives for full cardiac cycle dynamic anatomical guidance during interventional procedures, but also for 3DRA without need for very rapid pacing.

Indexed as

Catheter AblationRadiographic Image Interpretation, Computer-AssistedAlgorithmsArtifactsCardiac CatheterizationContrast MediaCoronary AngiographyFemaleFluoroscopyHumansMaleMiddle AgedMonte Carlo MethodRadiation DosageVentricular Dysfunction, LeftContrast Mediaangiographycatheter ablationimagingtomographyventricle

Identifiers

PMID26003152
PMCPMC4882875

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.