ReviewSocial psychiatry and psychiatric epidemiology2015
The Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort as a resource for studying psychopathology in childhood and adolescence: a summary of findings for depression and psychosis.
Review in Social psychiatry and psychiatric epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Longitudinal association between cardiovascular risk factors and depression in young people: a systematic review and meta-analysis of cohort studies.Psychological medicine · 2023Pooled it
- Psychiatric research in the Northern Finland Birth Cohort 1986 - a systematic review.International journal of circumpolar health · 2019Pooled it
- The systemic effects of 22q11.2 deletion syndrome on immunity.Journal of human immunity · 2026Review
- Youth psychotic experiences: psychometric evaluation and diagnostic associations of the CAPE-16 in adolescents from the Norwegian Mother, Father and Child Cohort.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Multimodal Prediction of Psychosis in the Prospective MoBa Birth Cohort.Research square · 2025Article
- Prenatal exposure to common infections and newborn DNA methylation: A prospective, population-based study.Brain, behavior, and immunity · 2024Article
- Psychological Impact of a Prenatal Diagnosis of Congenital Heart Disease on Parents: Is It Time for Tailored Psychological Support?Journal of cardiovascular development and disease · 2024Review
- Behavioural, psychiatric, and cognitive phenotypes associated with numbers of repeats of the FRAXE allele on the FMR2 gene.Wellcome open research · 2024Article
- The impact of cumulative obstetric complications and childhood trauma on brain volume in young people with psychotic experiences.Molecular psychiatry · 2023Article
- Psychosocial Basis of Human Sufferings and Poverty in Patients with Neurological and Psychiatric Disorders.Medical research archives · 2023Article
- The Mother-Baby Bond: Role of Past and Current Relationships.Children (Basel, Switzerland) · 2023Article
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- Epigenome-wide contributions to individual differences in childhood phenotypes: a GREML approach.Clinical epigenetics · 2022Article
- Parental Psychopathology and Oppositional Defiant Problems in Emerging Adults: Moderated Mediation by Temperament and Gender.Child psychiatry and human development · 2021Article
- Psychosis Risk and Development: What Do We Know From Population-Based Studies?Biological psychiatry · 2020Review
- Maternal perinatal depressive symptoms and offspring psychotic experiences at 18 years of age: a longitudinal study.The lancet. Psychiatry · 2020Article
- The anxious aspects of insecure attachment styles are associated with depression either in pregnancy or in the postpartum period.Annals of general psychiatry · 2020Article
- ResilienCity: Resilience and Psychotic-Like Experiences 10 Years After L'Aquila Earthquake.Frontiers in psychiatry · 2020Article
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Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
purposeThe purpose of this study is to highlight the Avon Longitudinal Study of Parents and Children (ALSPAC) as a resource to study psychopathology. To demonstrate this, we review the studies related to depression and psychosis in childhood and adolescence and discuss the results in relation to the aetiology of depression and psychotic experiences (PEs) and possible underlying mechanisms.
methodsWe examined the list of publications from ALSPAC and then classified them as examining (a) the course and risk factors of maternal and paternal depression, (b) the effects of maternal and paternal depression on child development, (c) risk factors for depression in childhood and adolescence, (d) the frequency, clinical relevance and risk factors of PEs, and (e) shared risk factors for depression and PEs.
resultsThere was evidence that environmental stressors and the way these are interpreted contribute to risk of depression and evidence that biological factors related to puberty are also likely to play a role. With regards to PEs, the findings further support the existence of 'a continuum of psychosis' while they also suggest that PEs might be of limited clinical utility in predicting psychotic disorder during adolescence and early adulthood. Finally, most risk factors examined were found to be shared between depression and PEs.
conclusionsThe ALSPAC birth cohort has provided important insights for our understanding of the aetiological mechanisms underlying depression and PEs. Future research could aim to incorporate measures of automatic psychological mechanisms to provide insights into the brain mechanisms that underlie these clinical phenomena.
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