Evidence map›Paper›PMID 26000642›Full record

ArticleRadiology2015

Feasibility of a Modified Cone-Beam CT Rotation Trajectory to Improve Liver Periphery Visualization during Transarterial Chemoembolization.

Rüdiger E Schernthaner, Julius Chapiro, Sonia Sahu, Paul Withagen, Rafael Duran, Jae Ho Sohn, Alessandro Radaelli, Imramsjah Martin van der Bom, Jean-François H Geschwind, MingDe Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Automatic bone removal for 3D TACE planning with C-arm CBCT: Evaluation of technical feasibility.Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rüdiger E SchernthanerFrom the Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital, 1800 Orleans St, Sheikh Zayed Tower, Suite 7203, Baltimore, MD 21287 (R.E.S., J.C., S.S., R.D., J.H.S., J.F.H.G.); Philips Healthcare, Best, the Netherlands (P.W., A.R., I.M.v.d.B.); and Department of Ultrasound and Interventions, Philips Research North America, Briarcliff Manor, NY (M.L.).
Julius ChapiroFrom the Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital, 1800 Orleans St, Sheikh Zayed Tower, Suite 7203, Baltimore, MD 21287 (R.E.S., J.C., S.S., R.D., J.H.S., J.F.H.G.); Philips Healthcare, Best, the Netherlands (P.W., A.R., I.M.v.d.B.); and Department of Ultrasound and Interventions, Philips Research North America, Briarcliff Manor, NY (M.L.).
Sonia SahuFrom the Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital, 1800 Orleans St, Sheikh Zayed Tower, Suite 7203, Baltimore, MD 21287 (R.E.S., J.C., S.S., R.D., J.H.S., J.F.H.G.); Philips Healthcare, Best, the Netherlands (P.W., A.R., I.M.v.d.B.); and Department of Ultrasound and Interventions, Philips Research North America, Briarcliff Manor, NY (M.L.).
Paul WithagenFrom the Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital, 1800 Orleans St, Sheikh Zayed Tower, Suite 7203, Baltimore, MD 21287 (R.E.S., J.C., S.S., R.D., J.H.S., J.F.H.G.); Philips Healthcare, Best, the Netherlands (P.W., A.R., I.M.v.d.B.); and Department of Ultrasound and Interventions, Philips Research North America, Briarcliff Manor, NY (M.L.).
Rafael DuranFrom the Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital, 1800 Orleans St, Sheikh Zayed Tower, Suite 7203, Baltimore, MD 21287 (R.E.S., J.C., S.S., R.D., J.H.S., J.F.H.G.); Philips Healthcare, Best, the Netherlands (P.W., A.R., I.M.v.d.B.); and Department of Ultrasound and Interventions, Philips Research North America, Briarcliff Manor, NY (M.L.).
Jae Ho SohnFrom the Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital, 1800 Orleans St, Sheikh Zayed Tower, Suite 7203, Baltimore, MD 21287 (R.E.S., J.C., S.S., R.D., J.H.S., J.F.H.G.); Philips Healthcare, Best, the Netherlands (P.W., A.R., I.M.v.d.B.); and Department of Ultrasound and Interventions, Philips Research North America, Briarcliff Manor, NY (M.L.).
Alessandro RadaelliFrom the Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital, 1800 Orleans St, Sheikh Zayed Tower, Suite 7203, Baltimore, MD 21287 (R.E.S., J.C., S.S., R.D., J.H.S., J.F.H.G.); Philips Healthcare, Best, the Netherlands (P.W., A.R., I.M.v.d.B.); and Department of Ultrasound and Interventions, Philips Research North America, Briarcliff Manor, NY (M.L.).
Imramsjah Martin van der BomFrom the Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital, 1800 Orleans St, Sheikh Zayed Tower, Suite 7203, Baltimore, MD 21287 (R.E.S., J.C., S.S., R.D., J.H.S., J.F.H.G.); Philips Healthcare, Best, the Netherlands (P.W., A.R., I.M.v.d.B.); and Department of Ultrasound and Interventions, Philips Research North America, Briarcliff Manor, NY (M.L.).
Jean-François H GeschwindFrom the Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital, 1800 Orleans St, Sheikh Zayed Tower, Suite 7203, Baltimore, MD 21287 (R.E.S., J.C., S.S., R.D., J.H.S., J.F.H.G.); Philips Healthcare, Best, the Netherlands (P.W., A.R., I.M.v.d.B.); and Department of Ultrasound and Interventions, Philips Research North America, Briarcliff Manor, NY (M.L.).
MingDe LinFrom the Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital, 1800 Orleans St, Sheikh Zayed Tower, Suite 7203, Baltimore, MD 21287 (R.E.S., J.C., S.S., R.D., J.H.S., J.F.H.G.); Philips Healthcare, Best, the Netherlands (P.W., A.R., I.M.v.d.B.); and Department of Ultrasound and Interventions, Philips Research North America, Briarcliff Manor, NY (M.L.).

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
See, Reach, Treat Tumor-Optimized Transarterial Chemoembolization DrugDeliveryR01CA160771 · NCI · YALE UNIVERSITY · PI GESCHWIND, JEAN-FRANCOIS H, LIN, MINGDE · 2011 to 2015
$2.6M
NCI NIH HHS P30 CA006973NCI NIH HHS R01 CA160771
6 · The paper itself

Abstract

purposeTo compare liver coverage and tumor detectability by using preprocedural magnetic resonance (MR) images as a reference, as well as radiation exposure of cone-beam computed tomography (CT) with different rotational trajectories. MATERIALS AND

methodsFifteen patients (nine men and six women; mean age ± standard deviation, 65 years ± 5) with primary or secondary liver cancer were retrospectively included in this institutional review board-approved study. A modified cone-beam CT protocol was used in which the C-arm rotates from +55° to -185° (open arc cone-beam CT) instead of -120° to +120° (closed arc cone-beam CT). Each patient underwent two sessions of transarterial chemoembolization between February 2013 and March 2014 with closed arc and open arc cone-beam CT (during the first and second transarterial chemoembolization sessions, respectively, as part of the institutional transarterial chemoembolization protocol). For each cone-beam CT examination, liver volume and tumor detectability were assessed by using MR images as the reference. Radiation exposure was compared by means of a phantom study. For statistical analysis, paired t tests and a Wilcoxon signed rank test were performed.

resultsMean liver volume imaged was 1695 cm(3) ± 542 and 1857 cm(3) ± 571 at closed arc and open arc cone-beam CT, respectively. The coverage of open arc cone-beam CT was significantly higher compared with closed arc cone-beam CT (97% vs 86% of the MR imaging liver volume, P = .002). In eight patients (53%), tumors were partially or completely outside the closed arc cone-beam CT field of view. All tumors were within the open arc cone-beam CT field of view. The open arc cone-beam CT radiation exposure by means of weighted CT index was slightly lower compared with that of closed arc cone-beam CT (-5.1%).

conclusionOpen arc cone-beam CT allowed for a significantly improved intraprocedural depiction of peripheral hepatic tumors while achieving a slight radiation exposure reduction.

Indexed as

AgedChemoembolization, TherapeuticCone-Beam Computed TomographyFeasibility StudiesFemaleHumansLiverLiver NeoplasmsMagnetic Resonance ImagingMaleRadiation ExposureRetrospective StudiesRotation

Identifiers

PMID26000642
PMCPMC4654716

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.