ArticleReproductive health2015
The impacts of maternal mortality and cause of death on children's risk of dying in rural South Africa: evidence from a population based surveillance study (1992-2013).
Article in Reproductive health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Risk of childhood mortality associated with death of a mother in low-and-middle-income countries: a systematic review and meta-analysis.BMC public health · 2019Pooled it
- Assessing the effectiveness of decentralised antenatal ultrasound in a primary health care clinic compared with a hospital-based service in rural South Africa: an interrupted time series analysis.BMC pregnancy and childbirth · 2025Article
- Article
- Child maltreatment mediates the relationship between HIV/AIDS family dysfunction trajectories and psychosocial problems among adolescents.PLOS global public health · 2023Article
- "There is no joy in the family anymore": a mixed-methods study on the experience and impact of maternal mortality on families in Ghana.BMC pregnancy and childbirth · 2022Article
- Building "Bridges" to Equity.American journal of public health · 2021Article
- Effect of timing of mother's death on child survival in a rural HIV hyper-endemic South African population.BMC public health · 2018Article
- Investigating risk factors for under-five mortality in an HIV hyper-endemic area of rural South Africa, from 2000-2014.PloS one · 2018Observational
- Socioeconomic differences in mortality in the antiretroviral therapy era in Agincourt, rural South Africa, 2001-13: a population surveillance analysis.The Lancet. Global health · 2017Article
- Pregnant and breastfeeding women: A priority population for HIV viral load monitoring.PLoS medicine · 2017Article
- Space-time patterns in maternal and mother mortality in a rural South African population with high HIV prevalence (2000-2014): results from a population-based cohort.BMC public health · 2017Article
- Risk factors and newborn outcomes associated with maternal deaths in the UK from 2009 to 2013: a national case-control study.BJOG : an international journal of obstetrics and gynaecology · 2016Article
- Survival of HIV-1 vertically infected children.Current opinion in HIV and AIDS · 2016Article
- Article
- The Effect of Maternal Death on the Health of the Husband and Children in a Rural Area of China: A Prospective Cohort Study.PloS one · 2016Article
- Social patterns and differentials in the fertility transition in the context of HIV/AIDS: evidence from population surveillance, rural South Africa, 1993 - 2013.Population health metrics · 2016Article
- The true cost of maternal death: individual tragedy impacts family, community and nations.Reproductive health · 2015Article
- "Without a mother": caregivers and community members' views about the impacts of maternal mortality on families in KwaZulu-Natal, South Africa.Reproductive health · 2015Article
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Authors and funding
5 authors at 4 institutions in 5 countries.
Funding
Abstract
backgroundMaternal mortality, the HIV/AIDS pandemic, and child survival are closely linked. This study contributes evidence on the impact of maternal death on children's risk of dying in an HIV-endemic population in rural South Africa.
methodsWe used data for children younger than 10 years from the Agincourt health and socio-demographic surveillance system (1992 - 2013). We used discrete time event history analysis to estimate children's risk of dying when they experienced a maternal death compared to children whose mother survived (N=3,740,992 child months). We also examined variation in risk due to cause of maternal death. We defined mother's survival status as early maternal death (during pregnancy, childbirth, or within 42 days of most recent childbirth or identified cause of death), late maternal death (within 43-365 days of most recent childbirth), any other death, and mothers who survived.
resultsChildren who experienced an early maternal death were at 15 times the risk of dying (RRR 15.2; 95% CI 8.3-27.9) compared to children whose mother survived. Children under 1 month whose mother died an early (p=0.002) maternal death were at increased risk of dying compared to older children. Children whose mothers died of an HIV/AIDS or TB-related early maternal death were at 29 times the risk of dying compared to children with surviving mothers (RRR 29.2; 95% CI 11.7-73.1). The risk of these children dying was significantly higher than those children whose mother died of a HIV/AIDS or TB-related non-maternal death (p=0.017).
conclusionsThis study contributes further evidence on the impact of a mother's death on child survival in a poor, rural setting with high HIV prevalence. The intersecting epidemics of maternal mortality and HIV/AIDS - especially in sub-Saharan Africa - have profound implications for maternal and child health and well-being. Such evidence can help guide public and primary health care practice and interventions.
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