Trial reportObstetrics and gynecology2015
Variation in Women's Understanding of Prenatal Testing.
Trial report in Obstetrics and gynecology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07077707 (A Randomized Trial of Chatbot for Prenatal Genetic Counseling), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Trial of Chatbot for Prenatal Genetic Counseling
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Couples experiences of receiving uncertain results following prenatal microarray or exome sequencing: A mixed-methods systematic review.Prenatal diagnosis · 2020Pooled it
- Impact of health literacy and primary language on the decision to pursue trial of labor after prior cesarean delivery.BMC pregnancy and childbirth · 2025Trial
- Reducing decisional conflict in decisions about prenatal genetic testing: the impact of a dyadic intervention at the start of prenatal care.Journal of perinatal medicine · 2024Trial
- Group vs traditional prenatal care for improving racial equity in preterm birth and low birthweight: the Centering and Racial Disparities randomized clinical trial study.American journal of obstetrics and gynecology · 2022Trial
- Use of a novel computerized decision aid for aneuploidy screening: a randomized controlled trial.Genetics in medicine : official journal of the American College of Medical Genetics · 2019Trial
- Improving Patient Knowledge of Aneuploidy Testing Using an Educational Video: A Randomized Controlled Trial.Obstetrics and gynecology · 2018Trial
- Sources and Level of Patient Knowledge Regarding Available Prenatal Diagnostic Methods and the Frequency of Their Use in the Polish Population.Healthcare (Basel, Switzerland) · 2025Article
- Are People From Black Communities Proportionately Represented in UK and US Studies Examining Views on Screening and Diagnostic Genetic Testing in Pregnancy? A Scoping Review.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Rethinking the Burden of Traditional Informed Consent Prior to Prenatal Genetic Screening.The Hastings Center report · 2025Article
- Disparities in access to reproductive genetic services associated with geographic location of residence and maternal race and ethnicity.Genetics in medicine : official journal of the American College of Medical Genetics · 2024Article
- Patient experiences with prenatal cell-free DNA screening in a safety net setting.Prenatal diagnosis · 2024Article
- Shortcomings of ethnicity-based carrier screening for conditions associated with Ashkenazi Jewish ancestry.Genetics in medicine open · 2024Article
- Clinician communication after discovery of a soft marker of aneuploidy during pregnancy: A mixed methods assessment of a communication workshop.Journal of gynecology obstetrics and human reproduction · 2023Article
- Understanding the experiences and perspectives of prenatal screening among a diverse cohort.Prenatal diagnosis · 2023Article
- Indications, types, and diagnostic implications of prenatal genetic testing in Sub-Saharan Africa: A descriptive study.PloS one · 2023Article
- Postpartum women's attitudes to disclosure of adult-onset conditions in pregnancy.Prenatal diagnosis · 2022Article
- Latinx individuals' knowledge of, preferences for, and experiences with prenatal genetic testing: a scoping review.Reproductive health · 2022Article
- "Being proactive, not reactive": exploring perceptions of genetic testing among White, Latinx, and Pacific Islander Populations.Journal of community genetics · 2021Article
- Pregnant Hispanic women's views and knowledge of prenatal genetic testing.Journal of genetic counseling · 2021Article
- Racial/Ethnic Disparities in the Burden of HIV/Cervical Cancer Comorbidity and Related In-hospital Mortality in the USA.Journal of racial and ethnic health disparities · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo investigate women's understanding of prenatal testing options and of their own experience with screening, diagnostic genetic testing, or both.
methodsThis was a secondary analysis of data from a randomized controlled trial of enhanced information and values clarification regarding prenatal genetic testing in the absence of financial barriers to testing. Women in the third trimester of pregnancy were asked whether they had discussed prenatal genetic testing with their health care providers, whether they understood this testing was optional, and whether they had undergone testing during their pregnancy. Multivariable logistic regression models were fit to determine independent predictors of these outcomes.
resultsData were available from 710 study participants. Discussions about screening tests were reported by 654 participants (92%); only 412 (58%) reported discussing diagnostic testing. That screening and diagnostic testing were optional was evident to approximately two thirds of women (n=470 and 455, respectively). Recall of actual tests undergone was correct for 626 (88%) for screening and for 700 (99%) for diagnostic testing. Racial, ethnic and socioeconomic variation existed in the understanding of whether screening and diagnostic tests were optional and in the correct recall of whether screening had been undertaken in the current pregnancy. In the usual care group, women receiving care in low-income settings were less likely to recall being offered diagnostic testing (adjusted odds ratio 0.23 [0.14-0.39]).
conclusionDisparities exist in women's recall of prenatal genetic testing discussions and their understanding of their own experience. Interventions that explain testing options to women and help clarify their preferences may help to eliminate these differences.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.