Evidence map›Paper›PMID 26000479›Full record

ReviewCell2015

The mechanical world of bacteria.

Alexandre Persat, Carey D Nadell, Minyoung Kevin Kim, Francois Ingremeau, Albert Siryaporn, Knut Drescher, Ned S Wingreen, Bonnie L Bassler, Zemer Gitai, Howard A Stone

Abstract readReview
In one paragraph

Review in Cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 233 papers.

0numbers the graph read from it
0cells of the map it votes in
233citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

233 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Micro-compression analysis of biopolymer-producing bacteria usingCell surface (Amsterdam, Netherlands) · 2026
    Article
  7. Article
  8. A cold-responsiveApplied and environmental microbiology · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Selective Trapping of Bacteria in Porous Media by Cell Length.Integrative and comparative biology · 2026
    Article
  16. Review
  17. Article
  18. ZnO Nanocrystals InhibitInternational journal of nanomedicine · 2026
    Article
  19. Article
  20. Article

173 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alexandre PersatDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.
Carey D NadellDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA; Max Planck Institute for Terrestrial Microbiology, 35043 Marburg, Germany.
Minyoung Kevin KimDepartment of Chemistry, Princeton University, Princeton, NJ 08544, USA.
Francois IngremeauDepartment of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ 08544, USA.
Albert SiryapornDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.
Knut DrescherMax Planck Institute for Terrestrial Microbiology, 35043 Marburg, Germany.
Ned S WingreenLewis Sigler Institute, Princeton University, Princeton, NJ 08544, USA.
Bonnie L BasslerDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
Zemer GitaiDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. Electronic address: zgitai@princeton.edu.
Howard A StoneDepartment of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ 08544, USA. Electronic address: hastone@princeton.edu.

Funding

Intra-and Inter-Species Communication in BacteriaR01GM065859 · NIGMS · PRINCETON UNIVERSITY · PI BASSLER, BONNIE L · 2002 to 2015
$4.2M
Mechano-microbiology: how physical forces control bacterial-host interactionsDP1AI124669 · NIAID · PRINCETON UNIVERSITY · PI GITAI, ZEMER · 2015 to 2019
$4.0M
Intra- and Inter- Species Communication in BacteriaR37GM065859 · NIGMS · PRINCETON UNIVERSITY · PI BASSLER, BONNIE L · 2016 to 2025
$3.4M
Caulobacter cell shape and cytoskeletal regulationR01GM107384 · NIGMS · PRINCETON UNIVERSITY · PI GITAI, ZEMER · 2013 to 2016
$1.5M
NIAID NIH HHS DP1 AI124669NIGMS NIH HHS R01 GM065859NIGMS NIH HHS R01GM065859NIGMS NIH HHS R01 GM107384NIGMS NIH HHS R37 GM065859
6 · The paper itself

Abstract

In the wild, bacteria are predominantly associated with surfaces as opposed to existing as free-swimming, isolated organisms. They are thus subject to surface-specific mechanics, including hydrodynamic forces, adhesive forces, the rheology of their surroundings, and transport rules that define their encounters with nutrients and signaling molecules. Here, we highlight the effects of mechanics on bacterial behaviors on surfaces at multiple length scales, from single bacteria to the development of multicellular bacterial communities such as biofilms.

Indexed as

Bacterial AdhesionBiofilmsBiological TransportBiomechanical PhenomenaEscherichia coliLocomotionPseudomonas aeruginosa

Identifiers

PMID26000479
PMCPMC4451180

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.