ArticleFrontiers in cellular and infection microbiology2015
Mouthguards: does the indigenous microbiome play a role in maintaining oral health?
Article in Frontiers in cellular and infection microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Influence of the long-term use of oral hygiene products containing stannous ions on the salivary microbiome - a randomized controlled trial.Scientific reports · 2020Trial
- Effects of Bifidobacterium probiotic on the treatment of chronic periodontitis: A randomized clinical trial.Journal of clinical periodontology · 2018Trial
- Diversity of the gut, vaginal and oral microbiome among pregnant women in South Africa with and without pre-eclampsia.Frontiers in global women's health · 2022Article
- Patterns of Oral Microbiota in Patients with Apical Periodontitis.Journal of clinical medicine · 2021Article
- Immunomodulatory streptococci that inhibit CXCL8 secretion and NFκB activation are common members of the oral microbiota.Journal of medical microbiology · 2021Article
- Grand Challenges in Oral Infections and Microbes.Frontiers in oral health · 2020Article
- Biogeography of the Oral Microbiome: The Site-Specialist Hypothesis.Annual review of microbiology · 2019Review
- Commensal and Pathogenic Biofilms Alter Toll-Like Receptor Signaling in Reconstructed Human Gingiva.Frontiers in cellular and infection microbiology · 2019Article
- Article
- Insights into human evolution from ancient and contemporary microbiome studies.Current opinion in genetics & development · 2016Review
- Smoking, pregnancy and the subgingival microbiome.Scientific reports · 2016Article
- A Modified Glycosaminoglycan, GM-0111, Inhibits Molecular Signaling Involved in Periodontitis.PloS one · 2016Article
- Exploring Relationships between Host Genome and Microbiome: New Insights from Genome-Wide Association Studies.Frontiers in microbiology · 2016Review
- Editorial: the oral microbiome in an ecological perspective.Frontiers in cellular and infection microbiology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The existence of symbiotic relationships between bacteria and their hosts in various ecosystems have long been known to science. The human body also hosts vast numbers of bacteria in several habitats. Emerging evidence from the gastro-intestinal tract, genito-urinary tract and respiratory indicates that there are several health benefits to hosting a complex and diverse microbial community. Bacteria colonize the oral cavity within a few minutes after birth and form stable communities. Our knowledge of the oral microbiome has expanded exponentially with development of novel exploratory methods that allow us to examine diversity, structure, function, and topography without the need to cultivate the individual components of the biofilm. The purpose of this perspective, therefore, is to examine the strength of current evidence supporting a role for the oral microbiome in maintaining oral health. While several lines of evidence are emerging to suggest that indigenous oral microbiota may have a role in immune education and preventing pathogen expansion, much more work is needed to definitively establish whether oral bacteria do indeed contribute to sustaining oral health, and if so, the mechanisms underlying this role.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.