ArticleFrontiers in microbiology2015
Changes in gene expression, cell physiology and toxicity of the harmful cyanobacterium Microcystis aeruginosa at elevated CO2.
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 49 citations in OpenAlex.
- Secondary metabolism ofApplied and environmental microbiology · 2026Review
- Impact of high temperature and UVR exposure on the microcystin production and mcyB gene expression in the cyanobacterium Microcystis aeruginosa.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025Article
- Effects of temperature up-shift and UV-A radiation on fatty acids content and expression of desaturase genes in cyanobacteria Microcystis aeruginosa: stress tolerance and acclimation responses.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024Article
- Metagenomic and Metatranscriptomic Insights into Population Diversity ofApplied and environmental microbiology · 2022Article
- Salt Shock Responses ofToxins · 2020Article
- Phenotypic plasticity of carbon fixation stimulates cyanobacterial blooms at elevated COScience advances · 2020Article
- An efficient and affordable laboratory method to produce and sustain high concentrations of microcystins byMethodsX · 2019Article
- Transcriptome Analysis of Phycocyanin-Mediated Inhibitory Functions on Non-Small Cell Lung Cancer A549 Cell Growth.Marine drugs · 2018Article
- Competition between cyanobacteria and green algae at low versus elevated CO2: who will win, and why?Journal of experimental botany · 2017Article
- Acclimation to High COPlant physiology · 2017Article
- Responses of the marine diatom Thalassiosira pseudonana to changes in COScientific reports · 2017Article
- Rapid adaptation of harmful cyanobacteria to rising CO2.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Diel Variation in Gene Expression of the CO2-Concentrating Mechanism during a Harmful Cyanobacterial Bloom.Frontiers in microbiology · 2016Article
- Strains of the Harmful Cyanobacterium Microcystis aeruginosa Differ in Gene Expression and Activity of Inorganic Carbon Uptake Systems at Elevated CO2 Levels.Applied and environmental microbiology · 2015Article
- Bloom Dynamics of Cyanobacteria and Their Toxins: Environmental Health Impacts and Mitigation Strategies.Frontiers in microbiology · 2015Review
- Acclimation of Synechocystis sp. PCC 6803 to Alkaline pH Under Ambient Air.Physiologia plantarumArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rising CO2 concentrations may have large effects on aquatic microorganisms. In this study, we investigated how elevated pCO2 affects the harmful freshwater cyanobacterium Microcystis aeruginosa. This species is capable of producing dense blooms and hepatotoxins called microcystins. Strain PCC 7806 was cultured in chemostats that were shifted from low to high pCO2 conditions. This resulted in a transition from a C-limited to a light-limited steady state, with a ~2.7-fold increase of the cyanobacterial biomass and ~2.5-fold more microcystin per cell. Cells increased their chlorophyll a and phycocyanin content, and raised their PSI/PSII ratio at high pCO2. Surprisingly, cells had a lower dry weight and contained less carbohydrates, which might be an adaptation to improve the buoyancy of Microcystis when light becomes more limiting at high pCO2. Only 234 of the 4691 genes responded to elevated pCO2. For instance, expression of the carboxysome, RuBisCO, photosystem and C metabolism genes did not change significantly, and only a few N assimilation genes were expressed differently. The lack of large-scale changes in the transcriptome could suit a buoyant species that lives in eutrophic lakes with strong CO2 fluctuations very well. However, we found major responses in inorganic carbon uptake. At low pCO2, cells were mainly dependent on bicarbonate uptake, whereas at high pCO2 gene expression of the bicarbonate uptake systems was down-regulated and cells shifted to CO2 and low-affinity bicarbonate uptake. These results show that the need for high-affinity bicarbonate uptake systems ceases at elevated CO2. Moreover, the combination of an increased cyanobacterial abundance, improved buoyancy, and higher toxin content per cell indicates that rising atmospheric CO2 levels may increase the problems associated with the harmful cyanobacterium Microcystis in eutrophic lakes.
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