ArticleFrontiers in microbiology2015
The antimicrobial activity of heterotrophic bacteria isolated from the marine sponge Erylus deficiens (Astrophorida, Geodiidae).
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
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- Presence of polyketide synthases and nonribosomal peptide synthetase in culturable bacteria associated with Aplysina fulva and Aplysina caissara (Porifera).Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Isolation and identification of antifungal, antibacterial and nematocide agents from marine bacillus gottheilii MSB1.BMC biotechnology · 2024Article
- Biosynthetic mechanism of the yellow pigments in the marine bacteriumApplied and environmental microbiology · 2024Article
- Exploring the biosynthetic gene clusters in Brevibacterium: a comparative genomic analysis of diversity and distribution.BMC genomics · 2023Article
- Advances in Natural Products from the Marine-Sponge-Associated Microorganisms with Antimicrobial Activity in the Last Decade.Marine drugs · 2023Review
- Exploring the Antibiotic Production Potential of Heterotrophic Bacterial Communities Isolated from the Marine SpongesMarine drugs · 2022Article
- Exploring Newer Biosynthetic Gene Clusters in Marine Microbial Prospecting.Marine biotechnology (New York, N.Y.) · 2022Review
- Marine Demospongiae: A Challenging Treasure of Bioactive Compounds.Marine drugs · 2022Review
- Factors affecting the isolation and diversity of marine sponge-associated bacteria.Applied microbiology and biotechnology · 2022Article
- Diversity of endophytic bacteria of mulberry (Frontiers in microbiology · 2022Article
- Identification of Sponge-Associated Bacteria From the Coast of Kuwait and Their Potential Biotechnological Applications.Frontiers in microbiology · 2022Article
- Microbial diversity in Mediterranean sponges as revealed by metataxonomic analysis.Scientific reports · 2021Article
- A Leap Forward Towards Unraveling Newer Anti-infective Agents from an Unconventional Source: a Draft Genome Sequence Illuminating the Future Promise of Marine Heterotrophic Bacillus sp. Against Drug-Resistant Pathogens.Marine biotechnology (New York, N.Y.) · 2021Article
- Marine Bacterial Secondary Metabolites: A Treasure House for Structurally Unique and Effective Antimicrobial Compounds.Marine drugs · 2021Review
- Bioactive Compounds from Marine Sponges: Fundamentals and Applications.Marine drugs · 2021Review
- AApplied and environmental microbiology · 2021Article
- A Neurotoxic Insecticide Promotes Fungal Infection in Aedes aegypti Larvae by Altering the Bacterial Community.Microbial ecology · 2021Article
- Antimicrobial Activities of Marine Sponge-Associated Bacteria.Microorganisms · 2021Article
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10 authors.
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Abstract
Interest in the study of marine sponges and their associated microbiome has increased both for ecological reasons and for their great biotechnological potential. In this work, heterotrophic bacteria associated with three specimens of the marine sponge Erylus deficiens, were isolated in pure culture, phylogenetically identified and screened for antimicrobial activity. The isolation of bacteria after an enrichment treatment in heterotrophic medium revealed diversity in bacterial composition with only Pseudoalteromonas being shared by two specimens. Of the 83 selected isolates, 58% belong to Proteobacteria, 23% to Actinobacteria and 19% to Firmicutes. Diffusion agar assays for bioactivity screening against four bacterial strains and one yeast, revealed that a high number of the isolated bacteria (68.7%) were active, particularly against Candida albicans and Vibrio anguillarum. Pseudoalteromonas, Microbacterium, and Proteus were the most bioactive genera. After this preliminary screening, the bioactive strains were further evaluated in liquid assays against C. albicans, Bacillus subtilis and Escherichia coli. Filtered culture medium and acetone extracts from three and 5 days-old cultures were assayed. High antifungal activity against C. albicans in both aqueous and acetone extracts as well as absence of activity against B. subtilis were confirmed. Higher levels of activity were obtained with the aqueous extracts when compared to the acetone extracts and differences were also observed between the 3 and 5 day-old extracts. Furthermore, a low number of active strains was observed against E. coli. Potential presence of type-I polyketide synthases (PKS-I) and non-ribosomal peptide synthetases (NRPSs) genes were detected in 17 and 30 isolates, respectively. The high levels of bioactivity and the likely presence of associated genes suggest that Erylus deficiens bacteria are potential sources of novel marine bioactive compounds.
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