ArticleFrontiers in microbiology2015
Antibacterial activity of endophytic fungi from leaves of Indigofera suffruticosa Miller (Fabaceae).
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 144 citations in OpenAlex.
- Metabarcoding Reveals Fungal Diversity in the Root and Rhizosphere ofInternational journal of microbiology · 2026Article
- Assessment of Antioxidant, Antimicrobial, and Cytotoxicity of Endophytic Fungi Isolated from the Root and Bark of Terminalia phanerophlebia (Engl. & Diels).Current microbiology · 2025Article
- Antifungal and enzymatic activities of endophytic fungi associated withPlant signaling & behavior · 2025Article
- Multifunctional bioactivity of eco-friendly Penicillium gladioli extract against Toxoplasma gondii and Pseudomonas aeruginosa.Scientific reports · 2025Article
- Efficacy ofInternational journal of molecular sciences · 2024Article
- Endophytic fungi ofSaudi journal of biological sciences · 2024Article
- Article
- Ovicidal and Pediculicidal Activity of Indigofera suffruticosa Mill. Leaf Oil on Pediculus humanus capitis Egg to Adult Stages.Acta parasitologica · 2023Article
- Antimicrobial Peptides: The Production of Novel Peptide-Based Therapeutics in Plant Systems.Life (Basel, Switzerland) · 2023Review
- Antimicrobial and Antioxidant Activities of Endophytic Fungi Associated withJournal of fungi (Basel, Switzerland) · 2023Article
- Multi-Function of a New Bioactive Secondary Metabolite Derived from Endophytic FungusJournal of microbiology and biotechnology · 2023Article
- Anti-inflammatory potential of Penicillium brefeldianum endophytic fungus supported with phytochemical profiling.Microbial cell factories · 2023Article
- Endophytic Fungi Isolated fromPlants (Basel, Switzerland) · 2023Article
- Diversity, chemical constituents and biological activities of endophytic fungi fromFrontiers in microbiology · 2023Article
- Diversity and Biological Activities of Endophytic Fungi from the Flowers of the Medicinal PlantInternational journal of molecular sciences · 2022Article
- Functional properties of Rhizopus oryzae strains isolated from agricultural soils as a potential probiotic for broiler feed fermentation.World journal of microbiology & biotechnology · 2022Article
- Antibacterial activity of peptaibols fromFrontiers in microbiology · 2022Article
- Potent Bioactivity of Endophytic Fungi Isolated fromBioMed research international · 2022Article
- The Neuroprotective Potential of Endophytic Fungi and Proposed Molecular Mechanism: A Current Update.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Silver Decorated Myconanoparticles Control Growth and Biofilm Formation in Uropathogenic E. coli.Applied biochemistry and biotechnology · 2022Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endophytic fungi were isolated from healthy leaves of Indigofera suffruticosa Miller, a medicinal plant found in Brazil which is used in folk medicine to treat various diseases. Among 65 endophytic fungi isolated, 18 fungi showed activity against at least one tested microorganism in preliminary screening, and the best results were obtained with Nigrospora sphaerica (URM-6060) and Pestalotiopsis maculans (URM-6061). After fermentation in liquid media and in semisolid media, only N. sphaerica demonstrated antibacterial activity (in Potato Dextrose Broth-PDB and in semisolid rice culture medium). In the next step, a methanolic extract from rice culture medium (NsME) and an ethyl acetate extract (NsEAE) from the supernatant of PDB were prepared and both exhibited antimicrobial activity against Gram-negative and Gram-positive bacteria. The best result was observed against Staphylococcus aureus, with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 1.56 mg/mL and 6.25 mg/mL, respectively, for NsME and MIC and MBC values of 0.39 mg/mL and 3.12 mg/mL, respectively, for NsEAE. This study is the first report about the antimicrobial activity of endophytic fungi residing in I. suffruticosa leaves, in which the fungus N. sphaerica demonstrated the ability to produce bioactive agents with pharmaceutical potential, and may provide a new lead in the pursuit of new biological sources of drug candidates.
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