ArticleFrontiers in human neuroscience2015
Altered resting-state EEG source functional connectivity in schizophrenia: the effect of illness duration.
Article in Frontiers in human neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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Who cites it
55 citing papers in PubMed, 118 citations in OpenAlex.
- Peripheral magnetic stimulation effects on brain activity in older adults with schizophrenia - a randomized controlled pilot study.Frontiers in psychiatry · 2026Trial
- Neurophysiological subtyping of schizophrenia reveals a reproducible phenotype with temporoparietal circuit disruptions.General psychiatry · 2026Article
- What Static Connectivity Misses: Dynamic Alpha-Band Brain Network States in First-Episode Psychosis.Brain topography · 2026Article
- Dopaminergic manipulation modulates frequency-specific EEG connectivity patterns: evidence from a single dose drug challenge study.Frontiers in neuroscience · 2026Article
- Electroencephalographic Biomarkers in Tinnitus: A Narrative Review of Current Approaches and Clinical Perspectives.Brain sciences · 2025Review
- Functional Connectivity Is Dominated by Aperiodic, Rather Than Oscillatory, Coupling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Resting-state EEG and MEG gamma frequencies in schizophrenia: a systematic review and exploratory power-spectrum metanalysis.Schizophrenia (Heidelberg, Germany) · 2025Review
- Functional Connectivity in Chronic Schizophrenia: An EEG Resting-State Study with Corrected Imaginary Phase-Locking.Brain and behavior · 2025Article
- EEG signatures of cognitive decline after mild SARS-CoV-2 infection: an age-dependent study.BMC medicine · 2024Article
- Minimum spanning tree analysis of EEG resting-state functional networks in schizophrenia.Scientific reports · 2024Article
- EEG hyperexcitability and hyperconnectivity linked to GABAergic inhibitory interneuron loss following traumatic brain injury.Brain communications · 2024Article
- Large-scale coupling of prefrontal activity patterns as a mechanism for cognitive control in health and disease: evidence from rodent models.Frontiers in neural circuits · 2024Review
- Pharmaco-EEG of antipsychotic treatment response: a systematic review.Schizophrenia (Heidelberg, Germany) · 2023Review
- Examining Neural Connectivity in Schizophrenia Using Task-Based EEG: A Graph Theory Approach.Sensors (Basel, Switzerland) · 2023Article
- Machine learning techniques in diagnostics and prediction of the clinical features of schizophrenia: a narrative review.Consortium psychiatricum · 2023Review
- Predicting Alcohol-Related Memory Problems in Older Adults: A Machine Learning Study with Multi-Domain Features.Behavioral sciences (Basel, Switzerland) · 2023Article
- Resting-State EEG Connectivity at High-Frequency Bands and Attentional Performance Dysfunction in Stabilized Schizophrenia Patients.Medicina (Kaunas, Lithuania) · 2023Article
- The EEG multiverse of schizophrenia.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Do we really measure what we think we are measuring?iScience · 2023Article
- Opposite Modulation of the NMDA Receptor by Glycine and S-Ketamine and the Effects on Resting State EEG Gamma Activity: New Insights into the Glutamate Hypothesis of Schizophrenia.International journal of molecular sciences · 2023Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 3 countries.
Funding
Abstract
Despite the increasing body of evidence supporting the hypothesis of schizophrenia as a disconnection syndrome, studies of resting-state EEG Source Functional Connectivity (EEG-SFC) in people affected by schizophrenia are sparse. The aim of the present study was to investigate resting-state EEG-SFC in 77 stable, medicated patients with schizophrenia (SCZ) compared to 78 healthy volunteers (HV). In order to study the effect of illness duration, SCZ were divided in those with a short duration of disease (SDD; n = 25) and those with a long duration of disease (LDD; n = 52). Resting-state EEG recordings in eyes closed condition were analyzed and lagged phase synchronization (LPS) indices were calculated for each ROI pair in the source-space EEG data. In delta and theta bands, SCZ had greater EEG-SFC than HV; a higher theta band connectivity in frontal regions was observed in LDD compared with SDD. In the alpha band, SCZ showed lower frontal EEG-SFC compared with HV whereas no differences were found between LDD and SDD. In the beta1 band, SCZ had greater EEG-SFC compared with HVs and in the beta2 band, LDD presented lower frontal and parieto-temporal EEG-SFC compared with HV. In the gamma band, SDD had greater connectivity values compared with LDD and HV. This study suggests that resting state brain network connectivity is abnormally organized in schizophrenia, with different patterns for the different EEG frequency components and that EEG can be a powerful tool to further elucidate the complexity of such disordered connectivity.
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