ReviewCurrent treatment options in infectious diseases
Dengue: Moving from Current Standard of Care to State-of-the-Art Treatment.
Review in Current treatment options in infectious diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Dengue diagnosis and impact on clinical management: A literature review.PLoS neglected tropical diseases · 2025Review
- Antiviral Efficacy of the Anesthetic Propofol against Dengue Virus Infection and Cellular Inflammation.Journal of immunology research · 2021Article
- Developing and using a dengue patient care guideline for patients admitted from households to primary care units and the district hospital: A community participatory approach in Southern Thailand.One health (Amsterdam, Netherlands) · 2020Article
- Clinical and Laboratory Profile of Fatal Dengue Cases at a Tertiary Care Private Hospital in Mumbai, India.The American journal of tropical medicine and hygiene · 2020Article
- Anti-inflammatory Compound Shows Therapeutic Safety and Efficacy against Flavivirus Infection.Antimicrobial agents and chemotherapy · 2019Article
- Effect OfIntegrative medicine (Encinitas, Calif.) · 2019Review
- Article
- Targeted Interventions in Critically Ill Children with Severe Dengue.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2018Article
- Dengue score as a diagnostic predictor for pleural effusion and/or ascites: external validation and clinical application.BMC infectious diseases · 2018Article
- Dengue and Zika viruses: lessons learned from the similarities between these Aedes mosquito-vectored arboviruses.Journal of microbiology (Seoul, Korea) · 2017Review
- DEAD-Box Helicase DDX25 Is a Negative Regulator of Type I Interferon Pathway and Facilitates RNA Virus Infection.Frontiers in cellular and infection microbiology · 2017Article
- Antioxidant and Intracellular Reactive Oxygen Species/Reactive Nitrogen Species Scavenging Activities of Three Porcupine Bezoars fromPharmacognosy researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Treatment of dengue remains supportive in the absence of targeted antiviral therapy or approved vaccines. Responsive fluid management is key to preventing progression to shock or other severe manifestations. The dynamic natural history of dengue infection and its influence on hemodynamic homeostasis needs to be carefully considered in the planning of individualized therapy. Though largely self-limiting, the sheer burden of dengue disease on the global population will result in atypical manifestations especially in children, older adults, and comorbid patients. Management of these has not yet been systematized. The failure of recent randomized controlled trials to show utility for antiviral and immunomodulatory agents in dengue is disappointing. Vaccine candidates hold promise, but growing outbreaks require more robust, evidence-based management guidelines to inform clinicians, especially in novel epidemic situations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.