Evidence map›Paper›PMID 25999765›Full record

ArticleInternational journal of women's health2015

Cervical cancer screening and treatment of cervical intraepithelial neoplasia in female sex workers using "screen and treat" approach.

Smita Joshi, Vinay Kulkarni, Trupti Darak, Uma Mahajan, Yogesh Srivastava, Sanjay Gupta, Sumitra Krishnan, Mahesh Mandolkar, Alok Chandra Bharti

Open access · goldAbstract read
In one paragraph

Article in International journal of women's health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Smita JoshiHirabai Cowasji Jehangir Medical Research Institute (HCJMRI), Jehangir Hospital Premises, Pune, Maharashtra, India.
Vinay KulkarniPrayas Health Group, Amrita Clinic, Pune, India.
Trupti DarakPrayas Health Group, Amrita Clinic, Pune, India.
Uma MahajanHirabai Cowasji Jehangir Medical Research Institute (HCJMRI), Jehangir Hospital Premises, Pune, Maharashtra, India.
Yogesh SrivastavaInstitute for Cytology and Preventive Oncology, Indian Council of Medical Research, New Delhi, India.
Sanjay GuptaInstitute for Cytology and Preventive Oncology, Indian Council of Medical Research, New Delhi, India.
Sumitra KrishnanHirabai Cowasji Jehangir Medical Research Institute (HCJMRI), Jehangir Hospital Premises, Pune, Maharashtra, India.
Mahesh MandolkarPrayas Health Group, Amrita Clinic, Pune, India.
Alok Chandra BhartiInstitute for Cytology and Preventive Oncology, Indian Council of Medical Research, New Delhi, India.
Amrita Therapeutics (India) · INIndian Council of Medical Research · INJehangir Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFemale sex workers (FSWs) are at an increased risk of human immunodeficiency virus (HIV) as well as human papillomavirus (HPV) infections and thus have an increased risk of cervical intraepithelial neoplasia (CIN) and cervical cancer. We evaluated the feasibility of "screen and treat approach" for cervical cancer prevention and the performance of different screening tests among FSWs.

methodsWomen were screened using cytology, VIA (visual inspection with acetic acid), and VILI (visual inspection with Lugol's iodine) and underwent colposcopy, biopsy, and immediate treatment using cold coagulation, if indicated, at the same visit.

resultsWe screened 300 FSWs of whom 200 (66.67%) were HIV uninfected and 100 (33.34%) were HIV infected. The overall prevalence of CIN 2-3 lesions was 4.7%. But all women with CIN 2-3 lesions were HIV infected, and thus the prevalence of CIN 2-3 lesions in HIV-infected FSWs was 14/100 (14%, 95% confidence interval: 7.2-20.8). All of them screened positive by all three screening tests. Cold coagulation was well tolerated, with no appreciable side effects.

conclusionCervical cancer prevention by "screen and treat" approach using VIA, followed by ablative treatment, in this high-risk group of women is feasible and can be implemented through various targeted intervention programs.

Indexed as

cervical cancerCINcold coagulationcytologyFSWsHPVVIAVILI

Identifiers

PMID25999765
PMCPMC4427081
OpenAlexW1710980402

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.