Evidence map›Paper›PMID 25999299›Full record

ArticleAnaerobe2015

Occurrence and new mutations involved in rifampicin-resistant Propionibacterium acnes strains isolated from biofilm or device-related infections.

Ulrika Furustrand Tafin, Guillaume Ghislain Aubin, Gerhard Eich, Andrej Trampuz, Stéphane Corvec

Abstract read
PubMed Publisher
In one paragraph

Article in Anaerobe, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

  1. In vitro emergence of amoxicillin-resistance and impact of amoxicillin on biofilm production across Cutibacterium acnes phylotypes?European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Cutibacterium namnetense osteosynthetic cervical spine infections: experience with two cases.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  3. Review
  4. Article
  5. The Impact of Surgical Strategy and Rifampin on Treatment Outcome in Cutibacterium Periprosthetic Joint Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. BMJ case reports · 2018
    Article
  11. Rifampin-ResistantJournal of bone and joint infection · 2018
    Article
  12. Article
  13. Article
  14. Article
  15. Unusual Case of Spondylodiscitis due toJournal of bone and joint infection · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Ulrika Furustrand TafinSeptic Surgical Unit, Department of Surgery and Anaesthesiology, Lausanne University Hospital, Lausanne, Switzerland.
Guillaume Ghislain AubinService de Bactériologie-Hygiène Hospitalière, Nantes University Hospital, Nantes, France; Université de Nantes, EA3826 Thérapeutiques cliniques et expérimentales des infections, Nantes Medicine School, F-44000 Nantes, France.
Gerhard EichInfectious Diseases Service, Zurich University Hospital, Zurich, Switzerland.
Andrej TrampuzCenter for Musculoskeletal Surgery, Charité - University Medicine Berlin, Berlin, Germany.
Stéphane CorvecService de Bactériologie-Hygiène Hospitalière, Nantes University Hospital, Nantes, France; Université de Nantes, EA3826 Thérapeutiques cliniques et expérimentales des infections, Nantes Medicine School, F-44000 Nantes, France. Electronic address: stephane.corvec@chu-nantes.fr.
Nantes Université · FRCharité - Universitätsmedizin Berlin · DEUniversity Hospital of Zurich · CHUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We described for the first time the amino acid substitutions conferring rifampicin resistance in eight Propionibacterium acnes strains isolated from patients with biofilm or device-related infections. We identified different mutations in cluster I and one mutation, never reported, in cluster II of the rpoB gene (I480V) associated with the most frequent one in cluster I (S442L). Half of the patients previously received treatment with rifampicin.

Indexed as

BiofilmsDrug Resistance, BacterialMutation, MissenseAdultAgedAged, 80 and overAmino Acid SubstitutionAnti-Bacterial AgentsCatheter-Related InfectionsDNA-Directed RNA PolymerasesFemaleGram-Positive Bacterial InfectionsHumansMaleMiddle AgedMolecular Sequence DataAnti-Bacterial AgentsDNA-Directed RNA PolymerasesRifampinRNA polymerase beta subunitBiofilmForeign-body infectionPropionibacterium acnesResistanceRifampicin

Identifiers

PMID25999299
OpenAlexW235987050

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.