Evidence map›Paper›PMID 25999040›Full record

ArticleSchizophrenia research2015

Demographic correlates of attenuated positive psychotic symptoms.

Rachel N Waford, Allison MacDonald, Katrina Goines, Derek M Novacek, Hanan D Trotman, Walker Elaine F, Jean Addington, Carrie E Bearden, Kristin S Cadenhead, Tyrone D Cannon and 8 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Schizophrenia research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 2 countries.

Rachel N WafordEmory University, Atlanta, GA 30322, USA. Electronic address: rwaford@emory.edu.
Allison MacDonaldEmory University, Atlanta, GA 30322, USA.
Katrina GoinesEmory University, Atlanta, GA 30322, USA.
Derek M NovacekEmory University, Atlanta, GA 30322, USA.
Hanan D TrotmanEmory University, Atlanta, GA 30322, USA.
Walker Elaine FEmory University, Atlanta, GA 30322, USA.
Jean AddingtonUniversity of Calgary, Calgary, Alberta, Canada.
Carrie E BeardenUniversity of California, Los Angeles, Los Angeles, CA, USA.
Kristin S CadenheadUniversity of California, San Diego, San Diego, CA, USA.
Tyrone D CannonYale University, New Haven, CT, USA.
Barbara A CornblattZucker Hillside Hospital, Great Neck, NY, USA.
Robert HeinssenNational Institute of Mental Health, Bethesda, MD, USA.
Daniel H MathalonUniversity of California, San Francisco, San Francisco, CA, USA.
Ming T TsuangUniversity of California, San Diego, San Diego, CA, USA.
Diana O PerkinsUniversity of North Carolina, Chapel Hill, Chapel Hill, NC, USA.
Larry J SeidmanBeth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Scott W WoodsYale University, New Haven, CT, USA.
Thomas H McGlashanYale University, New Haven, CT, USA.
Emory University · USYale University · USUniversity of California, San Diego · USHarvard University · USNational Institute of Mental Health · USUniversity of Calgary · CAUniversity of California, Los Angeles · USUniversity of California, San Francisco · USUniversity of North Carolina at Chapel Hill · USZucker Hillside Hospital · US

Funding

STRESS AND EMOTIONAL REACTIVITYP50MH066286 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI NUECHTERLEIN, KEITH H · 2003 to 2014
$18.6M
1/9 Predictors and Mechanisms of Conversion to PsychosisU01MH081902 · NIMH · YALE UNIVERSITY · PI CANNON, TYRONE D · 2008 to 2018
$12.4M
Vulnerability to Progression SchizophreniaP50MH080272 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI WOO, TSUNGUNG · 2007 to 2011
$9.9M
5/9 Predictors and Mechanisms of Conversion to PsychosisU01MH082004 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PERKINS, DIANA O. · 2008 to 2018
$7.5M
Administrative Supplement Harmonization of At Risk Multisite Observational Networks for Youth(HARMONY)U01MH081928 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI STONE, WILLIAM SETH · 2008 to 2018
$7.1M
4/9-Predictors and Mechanisms of Conversion to PsychosisU01MH081857 · NIMH · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI CORNBLATT, BARBARA A. · 2008 to 2018
$6.2M
8/9 Predictors and Mechanisms of Conversion to PsychosisU01MH082022 · NIMH · YALE UNIVERSITY · PI WOODS, SCOTT W · 2008 to 2018
$6.0M
2/9 - Predictors and Mechanisms of Conversion to PsychosisU01MH081988 · NIMH · EMORY UNIVERSITY · PI WALKER, ELAINE FRAN · 2008 to 2018
$5.4M
6/9-Predictors and Mechanisms of Conversion to PsychosisU01MH081944 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CADENHEAD, KRISTIN S. · 2008 to 2018
$4.9M
"7/9" Predictors and Mechanisms of Conversion to PsychosisU01MH081984 · NIMH · UNIVERSITY OF CALGARY · PI ADDINGTON, JEAN M · 2008 to 2018
$4.2M
VULNERABILITY MARKERS IN PRODROMAL SCHIZOPHRENIAR01MH060720 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CADENHEAD, KRISTIN S. · 2000 to 2010
$4.0M
9/9-Predictors and Mechanisms of Conversion to PsychosisU01MH076989 · NIMH · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI MATHALON, DANIEL H · 2014 to 2018
$3.9M
NIMH NIH HHS K24 MH076191NIMH NIH HHS K24MH76191NIMH NIH HHS MH081902NIMH NIH HHS P50 MH066286NIMH NIH HHS P50 MH080272NIMH NIH HHS R01 MH060720NIMH NIH HHS R01MH60720NIMH NIH HHS U01 MH076989NIMH NIH HHS U01 MH081857NIMH NIH HHS U01 MH081902NIMH NIH HHS U01 MH081928NIMH NIH HHS U01MH081928NIMH NIH HHS U01 MH081944NIMH NIH HHS U01 MH081984NIMH NIH HHS U01MH081984NIMH NIH HHS U01 MH081988NIMH NIH HHS U01MH081988NIMH NIH HHS U01 MH082004NIMH NIH HHS U01MH082004-01A1NIMH NIH HHS U01 MH082022NIMH NIH HHS U01MH082022NIMH NIH HHS UO1 MH081857-05PHS HHS SCDMH82101008006
6 · The paper itself

Abstract

It is now well established that the utilization of standardized clinical criteria can enhance prediction of psychosis. These criteria are primarily concerned with the presence and severity of attenuated positive symptoms. Because these symptom criteria are used to derive algorithms for designating clinical high risk (CHR) status and for maximizing prediction of psychosis risk, it is important to know whether the symptom ratings vary as a function of demographic factors that have previously been linked with symptoms in diagnosed psychotic patients. Using a sample of 356 CHR individuals from the NAPLS-II multi-site study, we examined the relation of three sex, age, and educational level, with the severity of attenuated positive symptom scores from the Scale of Prodromal Symptoms (SOPS). Demographic factors accounted for little of the variance in symptom ratings (5-6%). Older CHR individuals manifested more severe suspiciousness, and female CHR participants reported more unusual perceptual experiences than male participants. Contrary to prediction, higher educational level was associated with more severe ratings of unusual thought content, but less severe perceptual abnormalities. Overall, sex, age and education were modestly related to unusual thought content and perceptual abnormalities, only, suggesting minimal implication for designating CHR status and predicting psychosis-risk.

Indexed as

AdolescentAdultAge FactorsChildEducational StatusFemaleHumansLogistic ModelsLongitudinal StudiesMaleProdromal SymptomsPsychiatric Status Rating ScalesPsychotic DisordersSex FactorsYoung AdultEarly identificationEducationProdromePsychosisSex

Identifiers

PMID25999040
PMCPMC4767147
OpenAlexW1518516903

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.